Here we describe lentivirus-infected cell microarrays for the high-throughput screening of gene function in mammalian cells. To create these arrays, we cultured mammalian cells on glass slides ‘printed’ with lentiviruses pseudotyped as vesicular stomatitis virus glycoprotein, which encode short hairpin RNA or cDNA. Cells that land on the printed ‘features’ become infected with lentivirus, creat...

The development of the lung epithelium is regulated in a stepwise fashion to generate numerous differentiated and stem cell lineages in the adult lung. How these different lineages are generated in a spatially and temporally restricted fashion remains poorly understood, although epigenetic regulation probably plays an important role. We show that the Polycomb repressive complex 2 component Ezh2...

The endocannabinoid (EC) system consists of two main receptors: cannabinoid type 1 receptor cannabinoid receptors are found in both the central nervous system (CNS) and periphery, whereas the cannabinoid type 2 receptor cannabinoid receptor is found principally in the immune system and to a lesser extent in the CNS. The EC family consists of two classes of well characterised ligands; the N-acyl...

Adres do korespondencji: dr n. med. Aneta I. Gziut, Klinika Kardiologii Inwazyjnej, Centralny Szpital Kliniczny MSWiA, ul. Wołoska 137, 02-507 Warszawa, tel.: +48 22 508 11 00, faks: +48 22 508 11 77, e-mail: [email protected] Przedstawiamy przypadek 46-letniej chorej przekazanej ze szpitala rejonowego w ramach ostrego dyżuru hemodynamicznego ze wstępnym rozpoznaniem ostrego zes...

Charlotte Lerouge-Cohen, Souvenirs du passé perse à l’époque hellénistique (Arménie, Cappadoce, Commagène, Perside, Pont, Royaume arsacide), Peter Lang, Bruxelles 2022, pp. 502 + figs. 8 3 maps; ISBN 978-2-8076-1392-8

We consider a multimarket framework where a set of firms compete on two interrelated oligopolistic markets. Prior to competing in these markets, firms can spy on others in order to increase the quality of their product. We characterize the equilibrium espionage networks and networks that maximize social welfare under the most interesting scenario of diseconomies of scope. We find that in some s...