A bioassay of 4-chloro-m-phenylenediamine for possible carcinogenicity was conducted using Fischer 344 rats and B6C3F1 mice. 4-Chloro-m-phenylenediamine was administered in the feed, at either of two concentrations, to groups of 49 or 50 male and 50 female animals of each species. The dietary concentrations of 4-chloro-m-phenylediamine used in the chronic bioassay for low and high dose rats wer...

Kết quả nghiên cứu phổ hồng ngoại của DES điều chế cho thấy có sự hình thành tương tác liên kết hydrogen phân tử giữa L-proline và acid para-toluenesulfonic. Điều kiện thực hiện phản ứng tốt nhất thu được sau khi khảo sát: nhiệt độ 80oC, thời gian 120 phút, tỉ lệ benzaldehyde:o-phenylenediamine=2:1 (mmol) lượng xúc sử dụng là 30% mol so với o-phenylenediamine. Xúc thể 4 lần mà không thay đổi ho...

Synthesis of 3,1,5-benzoxadiazepines from the condensation of o-phenylenediamine (o-PDA) and acyl chlorides in the presence of a catalytic amount of various heteropolyacids (HPAs) is reported.

In this communication, we develop a novel fluorescent aptasensor for thrombin detection with the use of poly(m-phenylenediamine) (PMPD) rods as an effective sensing platform. This aptasensor exhibits extraordinarily high sensitivity with a detection limit as low as 100 pM and excellent selectivity.

p2o5-sio2 (30% w/w) was found to be a useful catalyst for the synthesis of various 2-substituted aryl benzimidazoles under solvent-less and in solvent conditions from o-phenylenediamine and aldehydes. the products were directly recrystallized from methanol.