Background. Few studies have measured, using validated scales, the psychosocial handicap of epilepsy in a general practice setting. Aim. To assess the prevalence of psychosocial problems associated with epilepsy. Method. A survey was undertaken of 309 subjects, with one or more non-febrile epileptic seizures, drawn from two general practices in the United Kingdom (UK). The outcome measures were...

To determine whether endothelin (ET) has a role in maintaining circulatory support during hypotensive hemorrhage, we (1) examined cardiac and systemic hemodynamics after a 6-mL hemorrhage in the presence and absence of the ETA receptor blocker BQ-123, (2) examined cardiac and systemic hemodynamics during BQ-123 infusion in nonhemorrhaged rats, (3) measured changes in circulating immunoreactive ...

The anticancer ruthenium complex trans-[tetrachlorobis(1Hindazole)ruthenate(III)], otherwise known as KP1019, has previously been shown to inhibit proliferation of ovarian tumor cells, induce DNA damage and apoptosis in colon carcinoma cells, and reduce tumor size in animal models. Notably, no doselimiting toxicity was observed in a Phase I clinical trial. Despite these successes, KP1019’s prec...

A Markov decision process model is developed to investigate the optimal scheduling of haul setting and retrievals on a factory trawler in the Pacific hake (Merluccius productus) fishery. The model was used to investigate changes in fishing behavior during a temporary ban on night fishing in 1992. The cycle of setting the net, fishing, and retrieving the net is modeled with different costs for e...

Dr Monllau is from the Hospital de la Sta Creu i Sant Pau, Drs Leal, Voss, and Pelfort are from the Hospitals del Mar i de l’Esperança, and Drs Monllau, Pelfort, and Tey are from the Institut Universitari Dexeus, Universitat Autònoma de Barcelona, Spain; and Dr Iñigo Pavlovich is from the Orthopedic Institute for Musculoskeletal Disorders, Hermosillo, Sonora, Mexico. Drs Monllau, Leal, Voss, Pe...

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This essay attempts a renewed, critical exposition of Husserl’s theory of the phenomenological reduction, incorporating manuscript material that has been published since the defining essays of the first generation of Husserl research. The discussion focuses on points that remain especially crucial, i.e., the concept of the natural attitude, the ways into the reduction (and their systematics), a...