Curriculum Change in South Africa Since 1994 The development of a national curriculum is a major challenge for any nation, and when a whole country depends on it to transform society in one broad stroke, it imposes tremendous expectations on such a curriculum. South Africa’s democratic government has inherited a divided and unequal system of education and must recognise that apartheid is not th...

In the present study, we evaluated the mechanisms of CDC42 in association with the microRNA-137 (miR-137)-induced inhibition of human hepatocellular carcinoma (HCC). The gene expression levels of miR-137 were evaluated in HCC cell lines. Direct association of miR-137 with its downstream target, cell division control protein 42 (CDC42), was evaluated by dual-luciferase assay, western blot analys...

microRNAs, frequently deregulated in human cancer, have been implicated in the progression of hepatocarcinogenesis. Here, we show that microRNA (miR)-137 is significantly down-regulated in hepatocellular carcinoma (HCC). Its decreased expression is associated with vein invasion, incomplete Involucrum, and distant metastasis. Multivariate analysis suggests that miR-137 is an independent indicato...

MicroRNA-137 (miR-137) was reported to be dysregulated in several human cancers. However, the function and mechanism of miR-137 in non-small cell lung cancer (NSCLC) is still unclear. In the current study, we explored the role of miR-137 in NSCLC progression. Using qRT-PCR, our data showed that miR-137 was significantly down-regulated in NSCLC tissues and cell lines. In vitro functional assay, ...

To track the long term bioaccumulation of (137)Cs in marine organisms off the Pacific Northwest coast of Canada, we developed a time dependent bioaccumulation model for (137)Cs in a marine mammalian food web that included fish-eating resident killer whales. The model outcomes show that (137)Cs can be expected to gradually bioaccumulate in the food web over time as demonstrated by the increase o...

Concentration of activity of Cs-137 and its spatial distribution in soils and lichen Hypogymnia physodes were determined in the Gorce Mts. (several hundred km2) in S Poland. The authors distinguished two areas of the Gorce Mts. on the basis of markedly different Cs-137 depositions, whose respective average values are 4.4 and 9.9 kBq/m2 as at 1st July 2005. The average Cs-137 activity concentrat...

BACKGROUND Oxidative stress, inducing cardiomyocyte apoptosis or myocardial ischemia, is the major denominator of many cardiac diseases. In this study, we intended to explore the regulatory function of microRNA-137 (miR-137) in oxidative stress-induced cardiomyocyte apoptosis. MATERIAL AND METHODS Cardiomyocytes were extracted from newborn C57BL/6 mice and cultured in vitro. Apoptosis was ind...

Concentration factors (CF: Bq.kg-1 in wet algae/Bq.kg-1 in filtered seawater) for Cs-137 in Japanese coastal algae, were investigated during 1984-1990. Cs-137/Cs(stable) atom ratios were also examined to clarify the distribution equilibrium of Cs-137 in marine algae and sea water. The CFs in marine algae were within the range of 5.4 approximately 92, and the geometric mean of CF was 28 +/- 2 (s...