نتایج جستجو برای: 15 after 2
تعداد نتایج: 3984452 فیلتر نتایج به سال:
Interleukin-15 receptor (IL-15R) and IL-2R have the same beta and gamma chains, but IL-15R has a specific alpha chain distinct from that of IL-2Ralpha, which is indispensable for the high affinity binding of IL-15. In the present study, we examined four IL-2-dependent adult T-cell leukemia (ATL) cell lines for their IL-15R expression. All cell lines bound IL-15, which was not inhibited by a 100...
Since its discovery in 1994, IL-15 has been studied in the context of its structural cousin, IL-2 (1). Early biochemical and in vitro lymphocyte studies revealed many similarities between IL-15 and IL-2: (a) IL-2 and IL-15 constitute the only two members of a family of cytokines containing a four a helix bundle; (b) the heterotrimeric receptors for IL-2 and IL-15 share both the IL-2/15R b and I...
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