Alcoholic extract of Kaempferia galanga was tested for analgesic and antiinflammatory activities in animal models. Three doses, 300 mg/kg, 600 mg/kg and 1200 mg/kg of the plant extract prepared as a suspension in 2 ml of 2% gum acacia were used. Acute and sub acute inflammatory activities were studied in rats by carrageenan induced paw edema and cotton pellet induced granuloma models respective...

Adverse drug reaction and resistance to antituberculosis drugs remain the causes of tuberculosis therapeutic failure. This research aimed to find the combination effect of standard antituberculosis drugs with Hibiscus sabdariffa L., Kaempferia galanga L., and Piper crocatum N.E. Br against multi-drug resistant (MDR) Mycobacterium tuberculosis isolates. Two MDR strains (i.e., isoniazid/ethambuto...

Rhizomes of Alpinia galanga (Linn.) or 'Kha' in Thai are used in food and as folk medicine in South and Southeast Asia. The aims of this study were to identify the mechanism of cell death of human leukemic HL-60 and U937 cells induced by 4'-hydroxycinnamaldehyde (4'-HCA) isolated from A. galanga. 4'-HCA was cytotoxic to both cell lines in a dose-dependent manner (p<0.05) as demonstrated by MTT ...

In the present work, the antiobesity effects of ethanol extract of Alpinia galanga rhizomes was evaluated in cafeteria diet fed obese rats. Obesity was induced in albino rats by feeding cafeteria diet daily for 6 weeks in addition to normal diet. The extract was administered at a daily dose of 400 mg/kg orally for 6 weeks. Body weight was measured initially and then every week thereafter. Indiv...

Psoriasis is a chronic inflammatory skin disorder characterized by rapid proliferation of keratinocytes and incomplete keratinization. Discovery of safer and more effective anti-psoriatic drugs remains an area of active research at the present time. Using a HaCaT keratinocyte cell line as an in vitro model, we had previously found that ethanolic extracts from three Thai medicinal herbs, namely ...

The people of District Sukoharjo in the Midle Java Province have traditionally use medicinal plants for maintaining their health and to cure illness by using what so called Jamu Gendong. verification, validation standardization these general, as yet, are not satisfactory. In order obtain better understanding this Gendong, Study Ethnobotany, Phytochemistry, Bioactivity has been carried out 3 Sub...

Labda-8 (17), 12-diene-15, 16-dial and coronarin E were isolated from the chloroform extract of the rhizomes of Alpinia javanica. The structures were elucidated spectroscopically. This is the first report of the isolation of coronarin E from Alpinia species. The distribution of these two labdane diterpenes within the Zingiberaceae is reported.

Objective: The objective of the study was to carry out phytochemical profiling essential oils (EOs) and evaluation their anti-microbial activity. Methods: EOs extracted from Cumminum cyminum, Zingiber officinale, Trachyspermum ammi, Alipnia galanga, Cedrus deodara, Elettaria cardamomum using clavenger apparatus. Phytochemical analysis high-performance thin layer chromatography (HPTLC) fingerpri...