نتایج جستجو برای: 177
تعداد نتایج: 9516 فیلتر نتایج به سال:
A systematic study of the modification of papain (its thiol group protected as a disulphide with mercaptoethanol) by N-bromosuccinimide, showed that 2 molar equiv. modified tryptophan-69 and 4 molar equiv. modified tryptophan-69 and -177. The Michaelis parameters for the catalysed hydrolysis of N-benzyloxycarbonylglycine p-nitrophenyl ester by these modified enzymes were determined. The enzymic...
روشهای درمانی مختلفی برای درمان سرطان پستان و متاستازهای آن ارائه شده است. درمان به روش ایمونوتراپی با آنتی بادی هرسپتین، یکی از موثر ترین روشهای درمانی در سرطان پستان است. هرسپتین با وجود موفقیت بسیار زیاد در درمان قطعی سرطان پستان، در 7-10 درصد بیماران ایجاد صدمات قلبی می کند. این مسئله زمانی پیچیده تر میشود که بیمار مبتلا به سرطان پستان دچار مشکل قلبی نیز باشد. یکی از مناسبترین روشهای درمانی...
BACKGROUND Metastatic bone lesion is a common syndrome of many cancer diseases in an advanced state. The major symptom is severe pain, spinal cord compression, and pathological fracture, associated with an obvious morbidity. Common treatments including systemic application of bisphosphonate drugs aim on pain reduction and on improving the quality of life of the patient. Particularly, patients w...
UNLABELLED Tumor vessels abundantly express receptors for vascular endothelial growth factor (VEGF), despite treatment with conventional or antiangiogenic drugs. We wished to determine whether the high levels of VEGF receptor (VEGFR) within the tumor vasculature could be leveraged for intracellular delivery of therapeutically significant doses of scVEGF/(177)Lu, a novel radiopharmaceutical base...
This study evaluated the effects of calf management following early weaning (EW) on growth and reproductive performance of beef heifers. On d 0, Brahman x British heifers (n = 40; body weight [BW] = 187 ± 37 lb; age = 69 ± 12 d) were stratified by age and BW, and randomly assigned to be normally-weaned on d 177 (NW), or 1 of 3 EW treatments: (1) EW and grazed on ryegrass pastures for 67 d then ...
During the last two decades, large-scale high biomass algal blooms of the dinoflagellate Prorocentrum donghaiense Lu have occurred frequently in the East China Sea (ECS). The role of increasing nutrient concentrations in driving those blooms is well-established, but the source population that initiates them is poorly understood. We hypothesized that the front of Taiwan Warm Current (TWC) may se...
3 Dedicated to my loving mother and wife for their love and constant support 4 ACKNOWLEDGMENTS First of all, I would like to appreciate my advisor and supervisory committee chair, Dr. Fan Ren. Thanks for his broad and profound knowledge, patience and encouragement through my Ph.D. study. The completion of this work would not be possible without the guidance from Dr. Fan Ren. He has always been ...
GRAPHICAL MODELS FOR PROTEIN FUNCTION AND STRUCTURE PREDICTION MINGJIE TANG,1,† KEAN MING TAN,2,† XIN LU TAN,2 LEE SAEL,1,3 MEGHANA CHITALE,1 JUAN ESQUIVEL-RODRÍGUEZ,1 and DAISUKE KIHARA1,3 1Department of Computer Science, Purdue University, West Lafayette, Indiana 2Department of Statistics, Purdue University, West Lafayette, Indiana 3Department of Biological Sciences, Purdue University, West L...
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