background fenton (fe2+ and h2o2) and modified fenton (fe3+ and h2o2) are two popular methods used in advanced oxidation processes (aop) and degradation of persistent organic pollutants (pops), such as dye compounds. in these processes, fe2+ and fe3+ as catalysts and h2o2 as the oxidizing agent are added to the reactor. objectives the aim of the current study is to assess the abovementioned met...

OBJECTIVES The purpose of this study was to investigate the prevalence of extended spectrum β-lactamase (ESBL) genes in Escherichia coli isolated from post-weaning diarrhea (PWD) piglets in Heilongjiang province, China. METHODS Of 458 E. coli isolated from 589 fecal samples from PWD piglets, a total of 198 isolates were confirmed as ESBL producers by the double-disk synergy test (DDST). Polym...

OBJECTIVE This study aimed to investigate whether the miR-198 expression level is related to clinicopathological factors and prognosis of esophageal cancer. METHODS MicroRNA was extracted from esophageal cancer patients who underwent surgery for assessment using the Taqman@ MicroRNA assay. The correlation between miR-198 expression and clinicopathological features was analyzed, and the signif...

Porcine epidemic diarrhea virus (PEDV) causes diarrhea of pigs age-independently and death of young piglets, resulting in economic loss of porcine industry. We have screened 333 natural oriental herbal medicines to search for new antiviral candidates against PEDV. We found that two herbal extracts, KIOM 198 and KIOM 124, contain significant anti-PED viral effect. KIOM 198 and KIOM 124 were iden...

PURPOSE The majority of pancreatic cancers overexpress mesothelin (MSLN), which contributes to enhanced proliferation, invasion, and migration. However, the MSLN regulatory network is still unclear. Here, we investigated the regulation of a panel of tumorigenic factors and explored the potential of MSLN-regulated miR-198 treatment in vivo. EXPERIMENTAL DESIGN The expression and functional reg...

Enterocytozoon bieneusi and Encephalitozoon spp. are microsporidian pathogens with zoonotic potential that pose significant public health concerns. To ascertain the occurrence genotypes of E. spp., we used nested PCR to amplify internal transcribed spacer (ITS) gene DNA sequencing analyze 198 fecal samples from red pandas 6 zoos in China. The total rate microsporidial infection was 15.7% (31/19...

BACKGROUND To examine the clinical value of miR-198-5p in lung squamous cell carcinoma (LUSC). METHODS Gene Expression Omnibus (GEO) microarray datasets were used to explore the miR-198-5p expression and its diagnostic value in LUSC. Real-time reverse transcription quantitative polymerase chain reaction was used to evaluate the expression of miR-198-5p in 23 formalin-fixed, paraffin-embedded ...

Unlike nuclear-targeted anthracyclines, the extranucleartargeted doxorubicin congener, N-benzyladriamycin-14valerate (AD 198), does not interfere with normal topoisomerase II activity, but binds to the C1b regulatory domain of conventional and novel isoforms of protein kinase C (PKC). The resulting interaction leads to enzyme activation and rapid apoptosis in a variety of mammalian cell lines t...

The effects of the interaction between cellularand tumor-scale processes on cancer progression and treatment response remain poorly understood (for instance, the crucial role of the microenvironment in cancer growth and invasion [95, 65, 184, 183, 160, 110, 66, 166]). Three-dimensional tissue morphology, cell phenotype, and molecular phenomena are intricately coupled; they influence cancer inva...