Many aspects of language comprehension are dependent on the identification of a perspectival/point-of-view anchor, who provides the perspectival center for interpreting the content of an utterance. To fully interpret epithets (ex.1a), evaluative adjectives (ex.1b), predicates of personal taste (ex.1c), epistemic modals (ex.1d) and adverbials of possibility (ex.1e), we need to know whose opinion...

.............................................................................................................................................24 Introduction........................................................................................................................................25 Section A................................................................................................

Cycloartenyl stearate (1a), lupenyl stearate (1b), sitosteryl stearate (1c), and 24-methylenecycloartanyl stearate (1d) (sample 1) from the air-dried leaves of Syzygium samarangense exhibited potent analgesic and anti-inflammatory activities at effective doses of 6.25 mg/kg body weight and 12.5 mg/kg body weight, respectively. Sample 1 also exhibited negligible toxicity on zebrafish embryonic t...

A 26-year-old woman was regularly followed up in a gastro-intestinal out-patient clinic. Since early childhood, she was noted to have hyperpigmented lesions over the perioral region (Fig 1a) and fingers (Fig 1b), and a history of small intestinal intussusception due to polyps that was treated by surgery when she was 12 years old. Endoscopic assessment revealed multiple gastric polyps (Fig 1c) a...

A 30-year old woman presented with neurological symptoms and a patent foramen ovale (PFO) that was closed with a Nit-Occlud® PFO. At the 6-month follow-up, the device was found in the aortic arch (Fig. 1A and B) and all efforts to retrieve it percutaneously were unsuccessful. Surgical intervention was indicated, the PFO directly closed (Fig. 1C) and the device removed under hypothermic circulat...

The nucleotide sequences of 59 bla(TEM) genes encoding inhibitor-resistant TEM enzymes showed great genetic variability and were associated with different types of promoters. These findings led us to suggest an updated bla(TEM) gene nomenclature based on the origin of the bla(TEM) gene (bla(TEM-1A), bla(TEM-1B), bla(TEM-1C), bla(TEM-1D), bla(TEM-1E), and bla(TEM-1F)) and the promoter type.

Wittig-Horner reagents 1a,b react with 1,2,3-indantrione (2) to give the dimeric adducts 3a and 3b, respectively. Moreover, 2 reacts with tert-butyl diethylphosphonoacetate (1c) yielding the ethylenic compound 4. On the other hand, 2 reacts with 1d to yield the phosphonate adduct 5. Mechanisms accounting for the formation of the new products are discussed and the probable structures of the prod...

Methods 15 patients with paroxysmal atrial fibrillation (PAF) underwent CMR scanning pre and immediately post WACA. 12 patients (4 male; mean age 56±11 years) had good quality images for delayed enhancement DE (necrosis) [Figure 1a,1b] and high T2-weighted signal (oedema) [Figure 1c,1d]. Images were analysed to quantify the circumferential extent of lesion formation with both imaging sequences....

Figure 1a. Contrast enhanced CT demonstrating a small calcified gallstone (arrow) within the gallbladder. 1b+c. Contrast enhanced CT two weeks later. b. A dilated gallbladder with thickened wall, absence of stone, and intrahepatic bile duct dilatation (arrow). 1c. The migrated gallstone (arrow) is seen in the distal CBD. 1d. ERCP demonstrating a filling defect in the distal CBD. 1e. The extract...

Ca2+ influx controls multiple neuronal functions including neurotransmitter release, protein phosphorylation, gene expression, and synaptic plasticity. Brain L-type Ca2+ channels, which contain either alpha 1C or alpha 1D as their pore-forming subunits, are an important source of calcium entry into neurons. Alpha 1C exists in long and short forms, which are differentially phosphorylated, and C-...