N-sulfonic acid pyridinium -4-carboxylic acid chloride {[Pyridine-N-SO3H-4-COOH]Cl} was synthesized, identified and applied as an effective catalyst for the preparation of pyrido[2,3-d:6,5-d]dipyrimidines by the condensation reaction of various aldehyde with 2-thiobarbituric acid and ammonium acetate under solvent-free conditions.The structure ofcatalyst was studied...

Aframomum melegueta Schum (Zingiberaceae) is a perennial herb widely cultivated for its valuable seeds in the tropical region of Africa. The present study evaluated the antioxidant effects of methanolic seed extract of A. melegueta. The antioxidant effects were evaluated using in vitro, 2, 2-diphenylpicrylhydrazine photometric assay and in vivo serum catalase, superoxide dismutase and thiobarbi...

The thiobarbiturates differ from other barbiturates in having a sulfur atom to replace the carbonyl oxygen at the C-2 position. The drug 2-thiobarbituric acid was soluble in 95% ethanol and 5% water for sensitive detection and measurement. All samples were examined at 340 nanometer wavelength. An ultraviolet-visible instrument with one centimeter glass cuvettes was suitable for this assay. The ...

Submit Manuscript | http://medcraveonline.com Abbreviations: DPPH: Diphenyl-2-Picryl Hydrazyl; NO: Nitric Oxide; SOD: Superoxide Anion; OH: Hydroxyl; NSAIDs: NonSteroidal Anti-Inflammatory Drugs; ROS: Reactive Oxygen Species; TBA: Thiobarbituric Acid; PMS: Phenazine Methosulphate; TPC: Total Phenolic

Background/Aim: We have previously reported the identification of cytotoxic chemotype compound-I (CC-I) from a chemical library screening against glioblastoma. Materials and Methods: The biological activity CC-I on drug-resistant neuroblastomas [e.g., HFE gene variant C282Y stably transfected human neuroblastoma SH-SY5Y cells (C282Y HFE/SH-SY5Y), SK-N-AS] was characterized using cell culture mo...

background and objectives: tree nuts and their oils contain bioactive materials which have vital roles in improving human’s health. degradation and decreasing the quality of the nuts especially in almond which have high fat is related to the oxidation. the quality of stored almond depends mainly on the kernel moisture and fat , storage temperature, relative humidity, oxygen level, type of packa...