Abdominal compartment syndrome (ACS) was originally described in trauma patients but is now known to occur in critically ill patients with a myriad of acute illnesses. Recent epidemiological studies have characterized the prevalence of intraabdominal hypertension (defi ned as an intraabdominal pressure [IAP] measured at the urinary bladder ≥12 mmHg) between 2% and 33% [1,2] and the prevalence o...

A45-year-old female presented with a 2-month history of numbness and tingling in her right hand. The symptoms, which were localized to the fingers, occurred throughout the day and wakened the patient at night. She reported that the symptoms were partially relieved by “shaking” her hand. The patient also reported weakness in her right hand, causing her difficulty in carrying her briefcase. Physi...

Migraine is a constellation of neurological symptoms with variable disease progression. Despite the standardization of migraine diagnosis with the International Headache Society (IHS) criteria, its etiology eludes medical research because its complexity as a disease lies in the multiple factors involved in migraine onset. The study of migraine genetics is providing important clues to the pathop...

Hereditary hemorrhagic telangiectasia (HHT) is caused by mutations in endoglin (ENG; HHT1) or ACVRL1/ALK1 (HHT2) genes and is an autosomal dominant vascular dysplasia. Clinically, HHT is characterized by epistaxis, telangiectases and arteriovenous malformations in some internal organs such as the lung, brain or liver. Endoglin and ALK1 proteins are specific endothelial receptors of the transfor...

Anakinra IL1 RA Open Safety and Tolerability Trial to Evaluate a Subcutaneous Injection Solution of 100 mg of Anakinra in Combination With Riluzol in Amyotrophic Lateral Sclerosis Unknown NCT01277315 II Interventional Safety/Efficacy Open label Treatment Charite University, Berlin Max Planck Institute for Infection Biology Germany Thomas Meyer 20 Subcutaneous Injection Solution of 100 mg of Ana...

Stroke is a leading cause of death and disability. Recent studies indicate that some degree of pituitary dysfunction may be observed after an acute stroke and this condition is commonly misdiagnosed. Reported here is the case of a 65 yearold man who developed symptoms of pituitary deficiency a few months after a frontal lobe stroke and finally presented with hypoglycemia and coma. Investigation...

49 Anakinra IL1 RA Open Safety and Tolerability Trial to Evaluate a Subcutaneous Injection Solution of 100 mg of Anakinra in Combination With Riluzol in Amyotrophic Lateral Sclerosis Unknown NCT01277315 II Interventional Safety/Efficacy Open label Treatment Charite University, Berlin Max Planck Institute for Infection Biology Germany Thomas Meyer 20 Subcutaneous Injection Solution of 100 mg of ...

Received Dec 26, 2014 Revised Feb 9, 2015 Accepted Feb 20, 2015 This paper proposes load-balancing algorithm on the basis of the Extended Dijkstra’s shortest path algorithm for Software Defined Networking (SDN). The Extended Dijkstra’s algorithm considers not only the edge weights, but also the node weights to find the nearest server for a requesting client. The proposed algorithm also consider...