INTRODUCTION Mismatch of diffusion/perfusion by MRI has been used as an estimate of the ischemic penumbra, but there are large parts of the mismatch region appear not to at risk, even though they may contribute to functional impairment (1). It was also reported that some of the apparent diffusion coefficient (ADC) reduction area can be salvaged by early reperfusion. It is essential to find a me...

Eighty patients with a total of 82 ischemic lesions were examined with contrast-enhanced MR imaging 1 hr to 1 month after onset of symptoms. The studies were reviewed retrospectively to determine the presence of arterial enhancement and the patterns of parenchymal enhancement. Arterial enhancement was often detected on the initial MR examination (45%), was frequently demonstrated in cortical in...

The effects of transient ischemia and reperfusion on regional myocardial function, salvage and swelling have been systematically analyzed in experimental canine preparations. The results of these interventions on myocardial in vitro measurements of magnetic relaxation times (T1 = magnetization recovery, T2 = spin echo) are of significant importance with respect to future nuclear magnetic resona...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 185 No. 2 235–249 www.jcb.org/cgi/doi/10.1083/jcb.200811138 JCB 235 Correspondence to Claudio Sette: [email protected]; or Stéphane Richard: [email protected] Maria Paola Paronetto’s present address is Centre de Regulaciò Genomica, Barcelona 08003, Spain. Abbreviations used in this paper: ANOVA, analysis of variance; dp...

Over the past two centuries human life expectancy has increased by nearly 50 years. Genetic factors account for about one-third of the variation in life expectancy so that most of the interindividual variation in lifespan is explained by stochastic and environmental factors, including diet. In some model organisms, dietary (energy) restriction is a potent, and highly reproducible, means of incr...

Since chest X-ray and CT scan features of Kaposi's sarcoma (KS) are nonspecific, we wanted to test the hypothesis that the histological components of this tumour and/or the associated haemorrhagic component, may result in a characteristic signal pattern on magnetic resonance imaging (MRI). Thoracic MRI was performed in a prospective manner in ten patients with acquired immune deficiency syndrom...

The normal neurohypophysis is hyperintense relative to brain and adenohypophysis on T1-weighted MR images, but the signal is not chemically shifted with respect to water. The source of the hyperintense MR signal in the normal neurohypophysis has been the subject of recent controversy. To date, an adequate biophysical explanation for the unusual imaging properties of the neurohypophysis has not ...

This study examines whether selective attention can influence sensory-discriminative aspects of nociception in humans and monkeys trained to detect innocuous and noxious thermal stimuli. Human subjects had two contact thermodes positioned bilaterally above the upper lip. Upon trial initiation both thermodes heated to either 39 degrees C, an innocuous warm temperature, or 45 degrees C, a slightl...

We analyze the footpoint separation d and ux asymmetry A of magnetically conjugate double footpoint sources in hard X-ray images from the Yohkoh Hard X-Ray Telescope (HXT). The dataset of 54 solar ares includes all events simultaneously observed with the COMPTON Gamma Ray Observatory (CGRO) in high-time resolution mode. From the CGRO data we deconvolved the direct-precipitation and trap-precipi...