The molecular and crystal structures of the title complex, [Ru(C 10 H 8 N 2 )(C 12 9 NO)(C 6 OS) ](CF 3 O S) or cis (S) ,trans (O, bpy )-[Ru(bpy)(ppk)(dmso- S ) ](OTf) {bpy = 2,2′-bipyridine, ppk phenyl-2-pyridyl ketone [IUPAC nomenclature: phenyl(pyridine-2-yl)methanone], dmso dimethyl sulfoxide, OTf − trifluoromethanesulfonate}, are reported. Ru 2+ ion has a distorted octahedral geometry with...

reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-sio2/hclo4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1h-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1h-pyrazol-5-ol derivatives in high yields.

Acute pharmacological blockade of central histamine H3 receptors (H3Rs) enhances arousal/attention in rodents. However, there is little information available for other behavioral domains or for repeated administration using selective compounds. ABT-239 [4-(2-{2-[(2R)-2-methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile] exemplifies such a selective, nonimidazole H3R antagonist with high aff...