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تعداد نتایج: 16882938 فیلتر نتایج به سال:
The differentiation deficiencies of osteoclast precursors (pre-OCs) may contribute to osteoporosis. Research on osteoporosis has recently focused on microRNAs (miRNAs) that play crucial roles in pre-OC differentiation. In the current study, we aimed to analyze the expression and function of the glucocorticoid (GC)-associated miRNA-338-3p (miR-338-3p) in osteoclast formation. We found that dexam...
Dysregulation of the epidermal growth factor receptor (EGFR) promotes cancer cell growth, invasion and metastasis. However, its relevant downstream effectors are still limited. Here, we show that EGFR promotes breast tumor growth and metastasis by downregulating the tumor suppressor micoRNA-338-3p (miR-338-3p) and activating the EYA2 (EYA transcriptional coactivator and phosphatase 2) oncoprote...
Under current law, national health expenditures are projected to grow at an average annual rate of 5.6 percent for 2016-25 and represent 19.9 percent of gross domestic product by 2025. For 2016, national health expenditure growth is anticipated to have slowed 1.1 percentage points to 4.8 percent, as a result of slower Medicaid and prescription drug spending growth. For the rest of the projectio...
BACKGROUND Human brain glioma is the most common endocranial tumor; its mortality and morbidity are very high. The objective of this study was to determine whether miR-338-3p can regulate malignant biological behaviors of glioma cells by targeted silencing of MACC1. MATERIAL AND METHODS The expression of miR-338-3p was detected by quantitative real-time PCR in brain glioma tissues and cell line...
Nasopharyngeal cancer (NPC) is an endemic type of head and neck cancer with a high rate of cervical lymph node metastasis. An increasing number of studies have shown that microRNAs (miRNAs) play a key role in the development and progression of NPC. miR-338-3p has been demonstrated as an anti-oncogene in different solid tumors. The aim of the present study was to investigate the potential role o...
MicroRNA-338-3p (miR-338-3p) has recently been reported to have anti-cancer efficacy in several types of cancers. However, its biological function and underlying mechanism involved in modulation of human non-small cell lung cancer (NSCLC) remain largely unknown. The present study was designed to investigate the function and underlying mechanism of miR-338-3p in human NSCLC tissues and cell line...
MicroRNAs (miRNAs) are a class of small, non-coding RNAs, which have demonstrated to important gene regulators, and have critical roles in diverse biological processes including cancer cell proliferation. Previous studies suggested microRNA-338-3p (miR-338-3p) was down-regulated and play tumor suppressor roles in gastric cancer, colorectal carcinoma and lung cancer. However, the role of miR-338...
Methods for estimating nonresponse bias are reviewed and several methods are tried on the 1980 GSS. The results indicate that various estimating procedures are inappropriate and that even the more promising techniques can provide faulty estimates of nonresponse bias. By its nature, nonresponse bias is very difficult to assess accurately and no simple, certain method exists. Tom W. Smith is Seni...
چکیده معضل چاقی به عنوان عارضه ای جدی برای زندگی بی تحرک و ماشینی، مورد توجه اغلب مراکز بهداشتی و درمانی دنیا قرار گرفته است. چاقی عامل زمینه ساز و در واقع عامل خطری برای بروز بیماری های قلبی - عروقی است که عموماً با کاهش طول عمر مورد انتظار و افزایش بیماری همراه است. هدف پژوهش حاضر تأثیر 12 هفته تمرینات ویبریشن کل بدن، تمرینات هوازی و تمرینات ترکیبی( هوازی و ویبریشن کل بدن) بر ترکیب بدنی زنان ...
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