نتایج جستجو برای: 367 1 micron
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CXXC finger protein 1 (Cfp1) is a regulator of both cytosine methylation and histone methylation. Murine embryonic stem (ES) cells lacking Cfp1 exhibit a decreased plating efficiency, decreased cytosine methylation, elevated global levels of histone H3-Lys4 trimethylation, and a failure to differentiate in vitro. Remarkably, transfection studies reveal that expression of either the amino half o...
Rationale: PIWI-interacting RNAs (piRNAs), a class of newly discovered small RNA molecules that function by binding to the Argonaute protein family (i.e., the PIWIL protein subfamily), and long noncoding RNAs (lncRNA) are implicated in several cancers. However, the detailed roles of ncRNAs in glioma remain unclear. Methods: The expression of PIWIL3, piR-30188, OIP5-AS1, miR-367, CEBPA and TRAF4...
Rationale: Angiogenesis is critical for embryonic development and microRNAs fine-tune this process, but the underlying mechanisms remain incompletely understood. Methods: Endothelial cell (EC) specific miR302-367 line was used as gain-of-function and anti-miRs as loss-of-function models to investigate the effects of miR302-367 on developmental angiogenesis with embryonic hindbrain vasculature a...
References http://rstb.royalsocietypublishing.org/content/367/1593/1213.full.html#related-urls Article cited in: http://rstb.royalsocietypublishing.org/content/367/1593/1213.full.html#ref-list-1 This article cites 71 articles, 34 of which can be accessed free Subject collections (109 articles) molecular biology (16 articles) microbiology (62 articles) biochemistry Articles on similar t...
References http://rstb.royalsocietypublishing.org/content/367/1594/1287.full.html#related-urls Article cited in: http://rstb.royalsocietypublishing.org/content/367/1594/1287.full.html#ref-list-1 This article cites 42 articles, 6 of which can be accessed free Subject collections (272 articles) neuroscience (208 articles) cognition (344 articles) behaviour Articles on similar topics can ...
The tracheae of ferrets and rabbits were mounted in vitro in organ baths. While the tracheae were liquid filled, the permeability coefficient ( P) was determined, and then while the tracheae were air filled, the percent clearance for 99mTc-labeled diethylenetriaminepentaacetic acid (DTPA) was determined. The thickness of airway surface liquid (ASL) was estimated by three methods. 1) The initial...
References http://rstb.royalsocietypublishing.org/content/367/1597/1879.full.html#related-urls Article cited in: http://rstb.royalsocietypublishing.org/content/367/1597/1879.full.html#ref-list-1 This article cites 115 articles, 14 of which can be accessed free This article is free to access Subject collections (497 articles) evolution (360 articles) ecology (357 articles) behaviour Art...
BACKGROUND Metastasis is one of the main reasons for treatment failure in endometrial cancer. Notably, high mobility group AT-hook 2 (HMGA2) has been recognized as a driving factor of tumour metastasis. microRNAs (miRNAs) are powerful posttranscriptional regulators of HMGA2. METHODS The binding sites of miR-302a-5p and miR-367-3p on HMGA2 mRNA were identified using bioinformatics prediction s...
A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.
In contrast to lower vertebrates, the mammalian heart has limited capacity to regenerate after injury in part due to ineffective reactivation of cardiomyocyte proliferation. We show that the microRNA cluster miR302-367 is important for cardiomyocyte proliferation during development and is sufficient to induce cardiomyocyte proliferation in the adult and promote cardiac regeneration. In mice, lo...
We measured intrapulmonary deposition of 0. 5-, 1-, 2-, and 3-micron-diameter particles in four subjects on the ground (1 G) and during parabolic flights both in microgravity (microG) and at approximately 1.6 G. Subjects breathed aerosols at a constant flow rate (0.4 l/s) and tidal volume (0.75 liter). At 1 G and approximately 1.6 G, deposition increased with increasing particle size. In microG...
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