Despite the wealth of information on the regulation of wild-type p53 function by phosphorylation, nothing is known about the biological effect of phosphorylation on mutant p53. Here we show that p53H175 is phosphorylated like wild-type p53 in cells of the same background. Ser(392) nonphosphorylatable p53 mutants p53H175A392 and p53W248A392 more potently transformed rat embryo fibroblasts in coo...

Polyclonal antibodies were produced and purified that selectively react with a p53 epitope containing the murine phosphoserine-389 or the human phosphoserine-392 residue, but not the unphosphorylated epitope. These antibodies, termed alpha-392, were employed to demonstrate that the phosphorylation of this serine-389 residue in the p53 protein occurs in vivo in response to ultraviolet radiation ...

The purpose of this study was to identify the prevalence of fungal colonization in water systems and to evaluate the effect of decreasing fungal colonization by a copper-silver ionization system. Environmental samples were collected for fungal culture prospectively during a 1-year period (2011-2012) at the study hospital. A total of 392 water samples were examined from five buildings on March 1...

Here, we demonstrate the first known approach to create G1 and G2 POSS dendrimers with 9 and 65 POSS units, and 56 and 392 terminal vinyl groups from a 1 → 7 branching monomer in only one and three steps.

INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386 Plan of experiment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 387 Frequency of primary non-disjunction after X-ray treatment. . . . . . . . . . . . . . . . . . . . . . . . . . 387 Phenotypic dis...

Review of Pons Jaume, M. (2021). El codi torbat. De la poesia experimental a l’escriptura conceptual . Palma de Mallorca: Lleonard Muntaner Editor, 392 pp.

1 Carbachol-induced long-term synaptic depression is enhanced during senescence at 2 hippocampal CA3-CA1 synapses 3 4 5 6 7 Ashok Kumar 8 Department of Neuroscience, McKnight Brain Institute, University of Florida, 9 Gainesville, FL 32610 10 11 12 13 Total number pages: 34 14 Number of figures: 7 15 Number of tables: 0 16 Word in the abstract: 167 17 Word in the introduction: 609 18 Word in the...

We have observed five quasars (0827+243, 0923+392, 1222+216, 1317+520, and 2209+080) with Chandra at 0.2-8 keV and with the VLA at 5 and 15 GHz. The X-ray emission is detected from all the radio jets except for 0923+392, whose double radio jet only extends out to the edge of the X-ray PSF. We model the spectral energy distribution of the jet features assuming that the X-ray emission originates ...