This RFC is not a candidate for any level of Internet Standard. The IETF disclaims any knowledge of the fitness of this RFC for any purpose and in particular notes that the decision to publish is not based on IETF review for such things as security, congestion control, or inappropriate interaction with deployed protocols. The RFC Editor has chosen to publish this document at its discretion. Rea...

ANYONE WHO HAS BEEN TO Prague in recent years will have enjoyed a vibrant restaurant industry. In addition to Czech restaurants whose sandwich boards beckon tourists with traditional Bohemian cuisine, one finds several exciting additions to the culinary scene: three Michelin-starred establishments, a multitude of international dining options, and a variety of choices for the vegetarians who, un...

Milk, meat and eggs tend not to be regarded as an important source of PUFA. They are disproportionally high in SFA compared with their PUFA content, especially those from cattle and sheep, since their rumen microbes are responsible for the loss of over 90 % of PUFA intake by livestock. This need not necessarily be the case since the relative proportion of PUFA in these foods is dictated by live...

In 1960, J. J. Gibson reviewed technical uses of the term stimulus and found that it did not have a consistent agreed-upon definition, but instead connoted several diVerent conceptions of ‘‘stimulating’’ an organism. Most of those conceptions did, however, have a property also found in the word’s original uses: A stimulus is a temporally discrete, momentary happening in the life of an organism....

chemistry Nitrosamines (NAs) are a family of chemical compounds discovered over 100 years ago. It was not until the 1950s that these compounds received worldwide attention. In the 1950s, two British scientists, Barnes and Magee discovered that dimethylnitrosamine is a powerful carcinogen in laboratory animals. This finding led to massive studies involving NAs in many industries throughout the y...

Synaptogenesis requires orchestrated intercellular communication between synaptic partners, with trans-synaptic signals necessarily traversing the extracellular synaptomatrix separating presynaptic and postsynaptic cells. Extracellular matrix metalloproteinases (Mmps) regulated by secreted tissue inhibitors of metalloproteinases (Timps), cleave secreted and membrane-associated targets to sculpt...