Recently, we reported that mutations in the neuropathy target esterase (NTE) gene cause autosomal recessive motor neuron disease (NTE-MND). We describe clinical, neurophysiologic, and neuroimaging features of affected subjects in the index families. NTE-MND subjects exhibited progressive lower extremity spastic weakness that began in childhood and was later associated with atrophy of distal leg...

Bela Bauer, Dave Wecker, Andrew J. Millis, Matthew B. Hastings, 2 and Matthias Troyer Station Q, Microsoft Research, Santa Barbara, CA 93106-6105, USA Quantum Architectures and Computation Group, Microsoft Research, Redmond, WA 98052, USA Department of Physics, Columbia University in the City of New York, New York, NY 10027 Theoretische Physik and Station Q Zurich, ETH Zurich, 8093 Zurich, Swit...

UNLABELLED Tetraploidy modifies root anatomy which may lead to differentiated capacity to uptake and transport mineral elements. This work provides insights into physiological and molecular characters involved in boron (B) toxicity responses in diploid (2x) and tetraploid (4x) plants of Carrizo citrange (Citrus sinensis L. Osb. × Poncirus trifoliata L. Raf.), a widely used citrus rootstock. Wit...

A characterization of critical sets and their images for suitable proper Whitney functions in the plane is given. More precisely, necessary and suucient conditions are provided for the existence of proper Whitney extensions F of f : C ! R 2 such that C is the critical set of F. This result relies strongly on theorems of Blank and Troyer.

Photosynthate partitioning was examined in seedings of sour orange (Citrus aurantium L.) and Carrizo citrange (Poncirus trifoliata [L.] Raf. x C. sinensis [L.] Osbeck) grown with split root systems inoculated on one side with vesicular-arbuscular mycorrhizal fungus (Glomus intraradices Schenck and Smith). Source-sink relations were studied without mitigating differences in mineral content or ph...

Carrizo citrange (Citrus sinensisxPoncirus trifoliata) is a citrus hybrid widely used as a rootstock, whose genetic manipulation to improve different growth characteristics is of high agronomic interest. In this work, transgenic Carrizo citrange plants have been produced overexpressing sense and antisense CcGA20ox1 (a key enzyme of GA biosynthesis) under control of the 35S promoter to modify pl...

Troyer syndrome is caused by a mutation in the SPG20 gene, which results in complete loss of expression of the protein spartin. We generated a genetic model of Troyer syndrome in worms to explore the locomotor consequences of a null mutation of the Caenorhabditis elegans SPG20 orthologue, F57B10.9, also known as spg-20. Spg-20 mutants showed decreased length, crawling speed, and thrashing frequ...

Citrus are one of the most relevant fruit crops in Mediterranean basin, which is second-highest citrus-growing region world. However, these mainly grown under semi-arid conditions, characterized by long periods drought and torrential rain. In this work, we have assessed response three promising HLB-tolerant citrus rootstocks (Orange-14, UFR-1, B11R3T27) to application four water stress conditio...