نتایج جستجو برای: 422
تعداد نتایج: 3233 فیلتر نتایج به سال:
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-1/2 (TRAIL-R1/R2), also known as death receptors, are expressed in a wide variety of tumor cells. Although TRAIL can induce cell apoptosis by engaging its cognate TRAIL-R1/R2, some tumor cells are or become resistant to TRAIL treatment. Monoclonal antibodies (mAbs) against TRAIL-R1/R2 have been developed to use as potentia...
We construct models of warped unification with a bulk SO(10) gauge symmetry and boundary conditions that preserve the SU(4)C×SU(2)L×SU(2)R Pati-Salam gauge group (422). In the dual 4D description, these models are 422 gauge theories in which the apparent unification of gauge couplings in the minimal supersymmetric standard model is explained as a consequence of strong coupling in the ultraviole...
Multirotor helicopters are increasingly popular platforms in the robotics community. Making them fully autonomous requires accurate state estimation. We review an improved dynamic model for multirotor helicopters and analyze the observability properties of an estimator based on this model. The model allows better use of IMU data to facilitate accurate state estimates even when updates from a se...
Previous reports have suggested that human CD4(+) CD25(hi)FOXP3(+) T regulatory cells (Tregs) have functional plasticity and may differentiate into effector T cells under inflammation. The molecular mechanisms underlying these findings remain unclear. Here we identified the residue serine 422 of human FOXP3 as a phosphorylation site that regulates its function, which is not present in murine Fo...
The causative agent of severe acute respiratory syndrome (SARS) is the SARS-associated coronavirus, SARS-CoV. The viral nucleocapsid (N) protein plays an essential role in viral RNA packaging. In this study, recombinant SARS-CoV N protein was shown to be dimeric by analytical ultracentrifugation, size exclusion chromatography coupled with light scattering, and chemical cross-linking. Dimeric N ...
Шнирельман В. Удерживающий. От Апокалипсиса к конспирологии. М., СПб.: Нестор-История, 2022. 422 с.
The polyhedral homotopy method, which has been known as a powerful numerical method for computing all isolated zeros of a polynomial system, requires all mixed cells of the support of the system to construct a family of homotopy functions. Finding the mixed cells is formulated in terms of a linear inequality system with an additional combinatorial condition. It is essential in computational eff...
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