We present phase-resolved spectroscopy of the optical counterparts V 801 Ara and V 926 Sco of the low-mass X-ray binaries 1636-536 and 1735-444. To assist in the interpretation of the spectroscopic observations we derive new ephemerides for the photometric variations of both sources. Superior conjunction of the line emission region occurs at photometric phase ∼0.7 in both sources, which indicat...

The EU regulation 536/2014 aims to facilitate the experimental use of diagnostic radiopharmaceuticals in particular for GMP requirements and needs to be applied in EU countries. As definitely clarified by this survey, the application is still far from being completed due to national restrictions that are conflicting with the content of the above EU regulation. Although the nuclear medicine cent...

The antibacterial activity of N-formimidoyl thienamycin was compared with those of cefotaxime, cefoperazone, and piperacillin against 536 clinical aerobic isolates.

Beich A, Thorsen T, Rollnick S. Screening in brief intervention trials targeting excessive drinkers in general practice: systematic review and meta-analysis. BMJ 2003;327:536–42 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

Plasma plasminogen is the precursor of the tumor angiogenesis inhibitor, angiostatin. Generation of angiostatin in blood involves activation of plasminogen to the serine protease plasmin and facilitated cleavage of two disulfide bonds and up to three peptide bonds in the kringle 5 domain of the protein. The mechanism of reduction of the two allosteric disulfides has been explored in this study....

routes of administration have been well documented, including avoidance of variable absorption rates and first-pass hepatic metabolism with oral delivery and improved therapeutic activity. In the past, skin penetration studies usually focused only on the physicochemical factors affecting the transport of drugs across the skin. However, recently, many researchers have also been considering the c...

The uropathogenic Escherichia coli strain 536 (O6:K15:H31) exhibits a mannose-resistant hemagglutination phenotype (Mrh) with bovine erythrocytes and delayed Mrh with human and guinea pig erythrocytes. Neuraminidase treatment of the erythrocytes abolishes mannose resistant hemagglutination, which is typical for X fimbriae. E. coli strain 536 synthesizes two different fimbriae (Fim phenotype) pr...

Nuclear factor B (NFB) plays an important role in regulating cellular transformation and apoptosis. The human T-cell lymphotropic virus type I protein, Tax, which is critical for viral transformation, modulates the transcription of several cellular genes through activation of NFB. We have demonstrated previously that Tax inhibits p53 activity through the p65/RelA subunit of NFB. We now present ...