The effects of D-tetrahydrocannabinol (D-THC; 0.3, 1, 3 and 10 mg/kg), and the fatty acid amide hydrolysis inhibitor URB-597 (0.1 and 0.3 mg/kg), on auditory and olfactory go/no-go discrimination tasks were examined in rats. The aims were to assess (i) whether simple olfactory and auditory discrimination tasks are sensitive to cannabinoid interference and (ii) whether manipulation of endogenous...

Abstract Aim To establish the prevalence of incivility within operating theatres, understand its impact on wellbeing, team performance, training, and direct future studies. Method A systematic search was conducted using keywords for in healthcare. Studies reporting from all theatre MDT members were included. Data extraction designed to incivility, compare experiences different specialties, asse...

The somatotropic axis, and particularly growth hormone-releasing hormone (GHRH), is implicated in the regulation of sleep-wake activity. To evaluate sleep in chronic somatotropic deficiency, sleep-wake activity was studied in dwarf (dw/dw) rats that are known to have a defective GHRH signaling mechanism in the pituitary and in normal Lewis rats, the parental strain of the dw/dw rats. In additio...

CRISPR-Cas (clustered regularly interspaced short palindromic repeats—CRISPR associated proteins) is a RNA-guided defense immune system that prevents some genetic elements such as plasmids and virus from getting into the bacterial cells. Zymomonas mobilis is an ethanologenic bacterium, which encodes a subtype I-F CRISPR-Cas system containing three CRISPR loci and a far distant cas gene cluster....

R. EASTELL, D.M. REID, J. COMPSTON, C. COOPER, I. FOGELMAN, R.M. FRANCIS, S.M. HAY, D.J. HOSKING, D.W. PURDIE, S.H. RALSTON, J. REEVE, R.G.G. RUSSELL1 and J.C. STEVENSON From the University of Sheffield Medical School, Sheffield, University of Aberdeen, Aberdeen, University of Cambridge School of Clinical Medicine, Addenbrooke’s Hospital, Cambridge, University of Southampton, Southampton, Guy’s...

Photosynthesis vs. irradiance relationships were determined for phytoplankton communities from seven lakes in the Canadian high Arctic, including ultraoligotrophic Char Lake, nutrient-enriched Meretta Lake, and two meromictic lakes. The derived photosynthetic parameters were low for all samples, with a mean (6SD) light-saturated photosynthetic rate (P ) of 0.46 (60.28) g C g21 chlorophyll a (Ch...

Nutritional value of freshwater mesozooplankton, fatty acid (FA) and amino acid (AA) compositions were determined in the middle of each season for a one-year period from May 2009 to February 2010 in Hanna Dam Lake, Isfahan, Iran. FA and AA composition significantly (P<0.05) varied in relation to the seasonal changes of water quality, phytoplankton and zooplankton community. The content of satur...

BACKGROUND AND PURPOSE Diffusion-weighted (DW) imaging has limited spatial resolution, especially in the z direction. We decreased the section thickness of DW imaging to 3 mm to determine if this change improves the depiction of small infarcts and if it affects stroke diagnosis. METHODS We studied conventional (5-mm section thickness, 1-mm intersection gap) and thin-section (3-mm section thic...