نتایج جستجو برای: 7 subjects
تعداد نتایج: 947546 فیلتر نتایج به سال:
Human subjects and rhesus monkeys receiving the antitumor agent methotrexate at the high dose levels recently introduced into clinical use (greater than 50 mg/kg) excrete significant amounts of the metabolite 7-hydroxymethotrexate. The metabolite is not detected in these species after methotrexate therapy at conventional dose levels. The evidence indicates that in primates, the in vivo conversi...
The study of the disappearance of the radioactivity in plasma after the injection of labeled aldosterone should elucidate the transport and metabolism of this steroid in man. In particular this would allow the calculation of the turnover rate in various clinical conditions. This value, together with a concomitant determination of the secretion rate estimated from the specific activity of a urin...
The P2X(7) receptor is a ligand-gated cation channel that is highly expressed on mononuclear leukocytes and that mediates ATP-induced apoptosis and killing of intracellular pathogens. There is a wide variation in P2X(7) receptor function between subjects, explained in part by four loss-of-function polymorphisms (R307Q, E496A, I568N, and a 5'-intronic splice site polymorphism), as well as rare m...
Previous animal studies have shown that angiotensin (Ang)-(1-7) is a biologically active component of the renin-angiotensin system, acting as a vasoactive agent, and may play a role in the blood pressure regulation. There is little information, however, on the effect of Ang-(1-7) on human circulation or the mechanism of its action. To investigate the effect of Ang-(1-7) on forearm circulation a...
The Smith-Lemli-Opitz syndrome (SLOS) is a multiple malformation/mental retardation syndrome caused by a deficiency of the enzyme 7-dehydrocholesterol Delta(7)-reductase. This enzyme converts 7-dehydrocholesterol (7-DHC) to cholesterol in the last step in cholesterol biosynthesis. The pathology of this condition may result from two different factors: the deficiency of cholesterol itself and/or ...
در این تحقیق تاثیر سه روش یادگیری لغات زبان دوم(ترکیبی- داخل متنو خارج متن) و تاثیر بسامد مواجه شدن با لغات که فاکتورهای مهمی در یادگیری زبان دوم هستند مورد بررسی قرار گرفتند. در این تحقیق از روشهای اماری paired-sampls t-testsو within-between subjects anova و pearson product moment correlation استفاده شد. نتایج نشان دادند که سه روش تاثیرات متفاوتی داشتند به طوریکه روش ترکیبی بهتر از روش داخل مت...
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