introduction: post-operative sore throat and cough are common complications of endotracheal intubation. these conditions may be very distressing for the patient and may lead to unpleasant memories. this study was performed in order to determine whether beclomethasone and lidocaine spray could reduce the frequency of post-operative sore throat and hoarseness after tracheal extubation.  materials...

BACKGROUND It is well known that opioids induce coughing. Many drugs such as lidocaine and ketamine are used to effectively prevent the coughing induced by opioids and this has been revealed to be effective. In this study, we evaluated the preventive effect of a graded escalation of the remifentanil concentration using a target controlled infusion pump and we compared this with the effect of li...

BACKGROUND Opiate is used in patient-controlled intravenous analgesia pumps (PCIA) for controlling pain in post-surgical patients. Other drugs are remarkably added to opioid pumps to enhance quality, lengthen analgesia, and reduce side effects. Lidocaine, a local anesthetic which inhibits sodium channels, has anesthetic and analgesic effects when injected locally or intravenously. The objective...

BACKGROUND Delivery of powder formulations to the nose is an attractive alternative for many drugs and vaccines. This study compared the regional nasal deposition and clearance patterns of lactose powder delivered by the OptiNose powder device (Opt-Powder; OptiNose US Inc., Yardley, PA, USA) to that of liquid aerosol administered via a traditional hand-actuated liquid spray pump (Rexam SP270, R...

INTRODUCTION Post-operative sore throat and cough are common complications of endotracheal intubation. These conditions may be very distressing for the patient and may lead to unpleasant memories. This study was performed in order to determine whether beclomethasone and lidocaine spray could reduce the frequency of post-operative sore throat and hoarseness after tracheal extubation. MATERIALS...

There are no conflicts of interest. midazolam versus Sufentanil‑midazolam for awake fiberoptic nasotracheal intubation: A randomized double‑blind study. effective dose of remifentanil for awake laryngoscopy and intubation. airway topical anesthesia in patients with a difficult airway: A randomized, double‑blind comparison of 2% and 4% lidocaine. Comparison of dexmedetomidine and sufentanil for ...

Correspondence To the Editor: In a single‑center, prospective, randomized double‑blind clinical study comparing dexmedetomidine‑ midazolam and sufentanil‑midazolam sedation regimens for awake fiberoptic intubation (AFOI) in 50 patients with difficult airways due to limited mouth opening, Li et al. show that both dexmedetomidine and sufentanil are effective as an adjuvant for AFOI under airway t...

Novel advanced spray-dried and co-spray-dried inhalable lung surfactant-mimic phospholipid and poly(ethylene glycol) (PEG)ylated lipopolymers as microparticulate/nanoparticulate dry powders of biodegradable biocompatible lipopolymers were rationally formulated via an organic solution advanced spray-drying process in closed mode using various phospholipid formulations and rationally chosen spray...