A major obstacle to the development of effective treatment of Alzheimer's disease (AD) is successfully delivery of drugs to the brain. We have previously identified a series of benzothiazole phosphonate compounds that block the interaction of amyloid-β peptide with amyloid-β binding alcohol dehydrogenase (ABAD). A selective and sensitive method for the presence of three new benzothiazole ABAD i...

Current strategies for the treatment of Alzheimer's disease (AD) involve tackling the formation or clearance of the amyloid-beta peptide (Aβ) and/or hyper-phosphorylated tau, or the support and stabilization of the remaining neuronal networks. However, as we gain a clearer idea of the large number of molecular mechanisms at work in this disease, it is becoming clearer that the treatment of AD s...

Several authors have presented methods to assess and derive the functional form of a single-attribute utility function based on the change in valuation of a lottery as the decision maker’s wealth increases (Abbas [1], Abbas and Aczél [2], Bell [7], Pfanzagl [9]). Bell [7] introduced and developed the idea of characterizing a utility function based on the maximum number of switches that may occu...

OBJECTIVE To determine the preparedness level of hospitals against natural disasters in Bandar Abbas, Iran. METHODS The cross-sectional, descriptive study was conducted in all the 9 hospitals in Bandar Abbas, Iran, during 2012. The required data was collected using a standard checklist comprising 220 items in 10 areas. It was completed for each hospital using observations and interviews. SPSS...

Levels of p53 protein as biomarker in plasma of workers exposed to carcinogenic polycyclic aromatic hydrocarbons Mehdi Zare a b c , Seyed Jamaleddin Shahtaheri a , Parvin Mehdipur d , Mohammad Shekari c e & Shahram Zare e a Department of Occupational Health Engineering, School of Public Health, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran b Departmen...

BACKGROUND The aim of this study was that the past five years data were collected to analyze the situation of malaria and health facilities in this area for better understanding malaria problem and to find solutions. METHODS In this retrospective study data of the last 5 years were obtained from health center of Bandar Abbas, published papers and reports, weather forecasting organization of t...

1 Department of Public Health, School of Health, Social Determinants in Health Promotion Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran 2 Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran 3 Department of Public Health, School of Health, Social Determinants in Health Promotion Research Center, Hormozgan University of Medical ...

COPD is a chronic multisystem disorder with various co morbidities. Smoking is a major risk factor. It’s etiology and multisystem effects may contribute to depression and anxiety. Interplay of various factors along with gender, socioeconomic, educational and marital status also do contribute to depression and anxiety in COPD. Unfortunately, Evaluation of anxiety and depression are often neglect...

Mild COPD is an asymptomatic disease but as oxidant antioxidant imbalance increases the severity of the disease also increases. The aim of the present study was to evaluate the oxidant antioxidant imbalance in mild and moderate COPD groups. The present study included 73 patients with COPD out of which 32 were of Mild impairment and 41 were suffering from Moderate COPD. The results indicated tha...