نتایج جستجو برای: abnormal retinal vessels
تعداد نتایج: 256742 فیلتر نتایج به سال:
Blood vessel in retinal image plays a vital role in medical diagnosis of many diseases. Diabetic retinopathy is one of the diseases which damages the retina and leads to blindness. Segmentation of blood vessels is helpful for ophthalmologists and this paper presents a new automatic method to extract blood vessels with high accuracy. This algorithm is comprised of optimized Gabor filter with loc...
uncontrolled hypertension is well- known to give rise to systemic complications involving multiple central organs. artherosclerosis leads to damage of the retinal vessels wall, contributing to venous stasis, thrombosis and finally, occlusion. retinal vein occlusions compromise vision through development of ischaemic maculopathy, macular oedema, and rubeotic glaucoma. laser photocoagulation rema...
Angiogenesis has an essential role in many pathophysiologies. Here, we show that phospholipase C-β3 (PLC-β3) isoform regulates endothelial cell function and retinal angiogenesis. Silencing of PLC-β3 in human umbilical vein endothelial cells (HUVECs) significantly delayed proliferation, migration and capillary-like tube formation. In addition, mice lacking PLC-β3 showed impaired retinal angiogen...
PURPOSE A neonatal mouse retina developmental model was used to study endothelial cell guidance and subsequent formation of vascular patterns. Since most diseases that cause catastrophic loss of vision do so as a result of abnormal ocular angiogenesis, a better understanding of events regulating normal retinal vascular growth may provide insight into pathologic angiogenesis. METHODS Developme...
During a 2-year period, 31 cases of a hereditary retinal degeneration in dogs bred in India were found mainly suspected for progressive retinal atrophy (PRA) with typical history of initial nyctalopia followed by hemeralopia. Out of 31 PRA suspected dogs, 8 dogs (26%) were from the age group of 1-5 years, 15 (48%) 6-10 years and the rest (26%) 11-15 years. The most predominant breed was Spitz (...
PURPOSE To investigate early retinal changes in a vascular endothelial growth factor (VEGF) transgenic mouse (tr029VEGF; rhodopsin promoter) with long-term damage that mimics nonproliferative diabetic retinopathy (NPDR) and mild proliferative diabetic retinopathy (PDR). METHODS Rhodopsin and VEGF expression was assessed up to postnatal day (P)28. Vascular and retinal changes were charted at P...
Diabetic Retinopathy-Scott et al. JOUM" haziness of the media in a large proportion of diabetics made it difficult to visualize the capillaries in this study. Although, in Fig. 6 B, an arterial injection of fluorescein has shown up zones of capillary closure alongside arteries and scattered small areas of capillary closure (Ashton, 1953), we have been able to discern this phenomenon in only thr...
BACKGROUND Vision loss due to vascular disease of the retina is a leading cause of blindness in the world. Retinal angiomatous proliferation (RAP) is a subgroup of neovascular age-related macular degeneration (AMD), whereby abnormal blood vessels develop in the retina leading to debilitating vision loss and eventual blindness. The novel mouse strain, neoretinal vascularization 2 (NRV2), shows s...
PURPOSE Retinopathy of prematurity (ROP) is a potentially blinding vasoproliferative disease. There is no standardized way to quantify plus disease (tortuous and dilated retinal vessels) or characterize abnormal recovery during ROP monitoring. This study objectively studies vascular features in live mice during development using noninvasive retinal imaging. METHODS Using fluorescein angiograp...
PURPOSE Recently, indocyanine green angiography (IA) was used to examine chorioretinal circulation in posterior uveitis in humans, and abnormal IA findings were reported. However, choroidal pathologic examination in conjunction with these abnormal IA findings has rarely been done. Experimental autoimmune uveoretinitis (EAU) is a model for posterior uveitis in humans. The purpose of this study w...
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