autoimmune hemolytic anemia (aiha) is characterized by shortening of red blood cell (rbc) survival and the presence of autoantibodies directed against autologous rbcs. approximately 20% of autoimmune hemolytic anemia cases are associated with cold-reactive antibody. about half of patients with aiha have no underlying associated disease; these cases are termed primary or idiopathic. secondary ca...

Coombs' positive hemolytic anemia is exceedingly rare in tuberculosis. We herein report a patient with tuberculosis associated with Coombs' positive hemolytic anemia that was responded to antituberculosis therapy. She was admitted to the hospital because of recent-onset fatigue, weakness, nonproductive cough, pallor and scleral jaundice. Coombs positive hemolytic anemia and pulmoner tuberculosi...

In the past, thrombotic thrombocytopenic purpura (TTP) was defined as a syndrome of the pentad of thrombocytopenia, microangiopathic hemolytic anemia, neurologic deficits, renal abnormalities and fever. To include patients with incomplete features, the pentad definition was replaced by the triad of thrombocytopenia, microangiopathic hemolytic anemia (MAHA), and neurologic deficits; or the diad ...

CUTE acquired hemolytic anemia is uncommon, but dramatic in its clinical picture and often disastrous in its outcome. In 1940, Dameshek and Schwartz’ assembled about ioo cases reported in the literature since 1907, in which no definite etiology was evident. In addition, as cited by these authors, cases have been reported in which the anemia developed in association with definite or probable eti...

Sex in Bacteria: Genetic Studies, 1945-1952: V'7 Joshua Lederberg and E. L. Tatum ............................ 169 aNew s and Notes ........... ......................... 175 Technical Papers A Criticism of the Indiscriminate Use of the SchmidtThannhauser Method for the Fractionation of Nucleic Acids in Biological Material: Marion L. Drasher . .......................................... 181 The O...

The purpose of this study was to determine whether the abnormal serum factors of acquired hemolytic anemia in patients with leukemia and lymphoma could be characterized as antibody by the immune adherence technique. The pathogenesis of this disorder has not been completely explained and it was felt that the study of specific immunologic reactions might help to determine whether these serum fact...

Warm antibody autoimmune hemolytic anemia is due to the presence of warm agglutinins that react with protein antigens on the surface of red blood cells causing premature destruction of circulating red blood cells. We report the first case of concurrent reactive arthritis, Graves' disease, and autoimmune hemolytic anemia. A 40-year-old man with reactive arthritis, Graves' disease, type 2 diabete...

Pulmonary hypertension (PH) has been reported with nearly all forms of the inherited as well as the acquired hemolytic anemias. Recent research investigating the pathophysiology of PH in sickle cell disease and thalassemia has helped elucidate the central role of hemolysis-mediated endothelial dysfunction in the development of PH in these populations. Although the most appropriate treatment of ...

glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most prevalent enzymopathy in mankind. it has sex-linked in­heritance. this enzyme exists in all cells.  g6pd deficiency increases the sensitivity of red blood cells to oxidative dam­age. g6pd deficiency was discovered in 1950 when some people suffered hemolytic anemia as a result of taking antimalar­ial drugs (primaquin). most people w...