Acrylic bone cements have been used for about 40 years to fix artificial prosthesis to bone structure. The properties of the acrylic bone cement mostly depend on the characteristics of the beads, which are the main component of the solid part of the cement. In this work beads of poly(methyl methacrylate-co-styrene) were synthesized by suspension polymerization. The objective of this study was t...

It has been suggested that the endurance of cemented femoral reconstructions in total hip arthroplasty is affected by the creep of acrylic cement, but it is not known to what extent cement creeps under loading conditions in vivo, or how this affects load transfer. We have simulated the long-term creep properties of acrylic cement in finite-element models of femoral stem constructs and analysed ...

2. Steinbrink K. T h e case for revislon arthroplasty u ing antibiotic-loaded acrylic cement. Clin Orthop Re1 Res 1990; 261: 19-22. 3. Gerhart TN, Roux RD, Hanff PA, Horowitz GL, Kenshaw AA, Hayes WC. Antibiotic-loaded biodegradable bone crmcnt for prophylaxis and treatment of experimental osteomyelitis in rats. J Orthop Res 19?3; 11: 250-5. 4. Reese RE, Betts RE Antibiotic use. In: Reese KE, B...

High-dose antibiotic-loaded acrylic cement (ALAC) is used for managing peri-prosthetic joint infections (PJIs). The marked increase in resistant high-virulence bacteria is drawing the attention of physicians toward alternative antimicrobial formulations loaded into acrylic bone cement. The aim of this in vitro study was to determine the elution kinetics of 14 different high-dose ALACs. All ALAC...

Artificial bone cements (BCs) based on poly(methyl methacrylate) (PMMA) powders and methyl methacrylate (MMA) liquid monomer also present in their formulation small amounts of other substances, including a chemical initiator compound and radiopaque agents. Because inadequate mixing of the recipe components during the manufacture of the bone cement may compromise the mechanical properties of the...

Objective: The aim of this study was to evaluate the efficacy of antibiotic-loaded bone cement in controlling local infection and in regard to its physical characteristics, elastic modulus, and tensile strength in-vitro. Methods: Acrylic bone cement, based on polymethylmethacrylate (PMMA) was mixed with the powder form of three antibiotics, i.e., gentamicin, tobramycin, and cefuroxime with diff...

Iodixanol (IDX) is a water soluble opacifier widely used in radiographical examinations of blood vessels and neural tissue, and it has been suggested as a potential contrast media in acrylic bone cement. The effect of the iodixanol particle size on the polymerisation process of the bone cement, the molecular weight, and the quasi-static mechanical properties have been investigated in this artic...

Previous studies have shown that the activity of the cytostatic drug methotrexate (MTX) embedded in acrylic cement is not affected by thermal changes in the cement. MTX is slowly released from the cement for several months and remains biologically active throughout this period. Our aim was to determine whether MTX embedded in cement would control the local growth of a tumour. In 15 rabbits we i...