نتایج جستجو برای: activated protein kinase
تعداد نتایج: 1443388 فیلتر نتایج به سال:
Our study was aimed at exploring the roles of lncRNA RP11-400K9.4 (RP11-400K9.4) on hypoxia/reoxygenation (H/R) -induced cardiomyocytes apoptosis. H/R model constructed in rat primary (PC) and H9c2 cells. In this study, results showed that significantly induced apoptosis PC The expression upregulated H/R-induced cells, but miR-423 downregulated. Silencing could attenuate We also found a potenti...
Alzheimer's disease (AD) is a degenerative brain with complex clinical manifestations and pathogeneses such as abnormal deposition of beta-amyloid protein inflammation caused by the excessive activation microglia. CXC motif chemokine receptor type 4 (CXCR4) G protein-coupled that binds to ligand 12 (CXCL12) activate downstream signaling pathways, Janus kinase/signal transducer activator transcr...
Oxymatrine, a potent monosomic alkaloid extracted from Chinese herb Sophora japonica (Sophora flavescens Ait.). possesses anti-inflammatory activittyes. This study was designed to investigate the effects of oxymatrine on nuclear factor–kappa B (NF-κB) and mitogen-activated protein kinase (MAPK)-dependent inflammatory responses in lipopolysaccharide (LPS)-activated microglia. In this paper, BV2...
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