Surgical treatment is often accompanied by such complication as bleeding, and ophthalmic surgery not an exception. The bleeding risk depends on many factors, the most significant are age, arterial hypertension, hepatic renal impairment, prior stroke or with oral anticoagulants. aim. To evaluate structure of patients taking novel anticoagulants (NOACs) assessment activated partial thromboplastin...

We report on a 57-year-old woman with a pontine haemorrhage and an extremely prolonged activated partial thromboplastin time (aPTT) of more than 240 s, suggestive of a coagulation disorder. Given the location of the haemorrhage, which is associated with a high mortality rate, recombinant factor VIIa was administered, although not all necessary laboratory analyses could be performed at that time...

Exposure to cement dust has been serious public health concern with increasing industrial activities in Port Harcourt. This study was aimed at evaluating the effect of exposure on haemostatic parameters loaders A total 200 healthy males were recruited for study; 100 which and other individuals not exposed dust. These subjects selected randomly different depot Harcourt after consenting participa...

BACKGROUND Bleeding time has been used for a long time as a global test of platelet function. Due to a number of pitfalls the test has been losing popularity. This study was designed to determine the prevalence of prolonged bleeding time in Nigerians with chronic liver disease in relation to other indices of hemostasis. METHODS Bleeding time, platelet count, prothrombin time (PT) and activate...

Hemolyzed specimens are rejected for coagulation testing based on concerns of artifactual interference. Prothrombin time (PT), activated partial thromboplastin time (aPTT), and selected factor assay test results for consecutive pairs of hemolyzed and subsequently recollected (mean, 72 minutes later) nonhemolyzed patient specimens were compared. Specimens from healthy human subjects were subject...

OBJECTIVE To determine the optimum storage temperature and time for prothrombin time and activated partial thromboplastin time at various intervals at both room temperature and refrigerator. STUDY DESIGN Experimental study. PLACE AND DURATION OF STUDY Advanced Medical and Dental Institute (AMDI), Laboratory at University Sains Malaysia (USM), from August 2009 to June 2010. METHODOLOGY Aft...

Haemostasis is a physiological process that prevents excessive blood loss. In laboratory, the prothrombin time (PT) and the activated partial thromboplastin time (aPTT) are used to examine clotting systems. However, the influence of sex on PT and aPTT values is unknown. The present work aimed to determine the values for PT and aPTT in adult sheep and to evaluate their dependence on the sex of t...

Factor XII, (Hageman factor) is a serine protease zymogen that, when activated, initiates the intrinsic pathway of blood coagulation. Patients with Factor XII deficiency do not have excessive bleeding tendency despite prolongation of the activated partial thromboplastin time (APTT) in their serum. Postpartum Hemorrhage (PPH) is a potentially fatal obstetric complication, and its presence in the...

Abbreviations: ACT 5 activated clotting time; APTT 5 activated partial thromboplastin time; AT 5 antithrombin; AT-III 5 antithrombin III; CI 5 confidence interval; DVT 5 deep vein thrombosis; GP 5 glycoprotein; HIT 5 heparininduced thrombocytopenia; INR 5 international normalized ratio; LMWH 5 low-molecular-weight heparin; MI 5 myocardial infarction; NQMI 5 non-Q-wave myocardial infarction; OR ...