objective(s): to study the effect of cardiopulmonary bypass (cpb) on nuclear factor-kappa b (nf-кb) and cytokine expression and pulmonary function in dogs. materials and methods: twelve male mongrel dogs were divided into a methylprednisolone group (group m) and a control group (group c). all animals underwent aortic and right atrial catheterization under general anesthesia. changes in pulmonar...

The main effectors of apoptosis are proteases belonging to the caspase family. Caspases represent key mediators in the initiation and execution of the apoptotic program. The apoptotic caspases constitute a minimal two-step signaling pathway that culminates in the controlled demise of the affected cell. At the center of intense research for more than a decade and a half, a thorough picture of th...

multiple sclerosis (ms) is a complex neurological disease and its prevalence is about 2 million in the world. neuroinflammation plays a key role in ms. vitamins are essential nutrients that have effective role on immune system including activation of lymphocyte and differentiation of t-helper cell. vitamin d is a micronutrient that is effective on immune function. deficiently of vitamin d is a ...

The rate of hydrolysis of trans -[Cr(NH ) F ] was obtained as a function of acid concentsation in perchloric, sulfuric and nitric acid at 3Q°C. The results have been analyzed by the treatment of Bunnett and Olsen. Values of the parameter ?in Olsen equation are consistent with the participation of water as a proton-wansfer agent in the rate-determining step. The Arrhenius plot for perchlori...

conclusions in this study, the l-lps immune response of bovine cells was significant, indicating that tlr2 is the predominant receptor for l-lps. due to l-lps endotoxin-like activity, we found a strategy through using bmap-28 to prevent l-lps-induced tlr2-dependent immune activation in bovine cells. materials and methods in this study, l-lps-induced proinflammatory cytokine production in bovine...