Platelet activation has a critical role in arterial disorders. In this study, we showed that the upregulation of P-selectin expression on platelets was related with clinical worsening in acute ischemic stroke. We serially (within 24 hr, at 72 hr, and 7 days) measured the expression of P-selectin on platelets in patients with acute ischemic stroke (n=45) and investigated the correlation between ...

Introduction: Stroke is known as a common cause of disability all over the world. Stroke prognosis estimation has always been a topic of interest. In this study, it was tried to investigate the prognostic value of laboratory findings of complete blood count in a systematic review. Methods: In this systematic review, literature from Medline via (PubMed, Ovid) Embase, Scopus, Cochrane Library, a...

background: as yet migraine has been established as one of the risk factors for ischemic stroke. some of the factors have been assessed for the explanation of this relation. hyperhomocysteinemia is seen partly both in stroke and in migraine. this study was conducted to determine the mean plasma levels of homocysteine in ischemic stroke patients on the basis of migraine history.methods: this cro...

OBJECTIVE To study the relationship between dyslipidemia and outcome in patients with acute ischemic stroke. METHODS Data about 1 568 patients with acute ischemic stroke were collected from 4 hospitals in Shandong Province from January 2006 to December 2008. National Institute of Health Stroke Scale (NIHSS) >10 at discharge or death was defined as the outcome. Effect of dyslipidemia on outcom...

BACKGROUND Stroke is a common presentation in geriatric patients in emergency department but rarely seen in pediatric patients. In case of acute ischemic stroke in pediatric age group, management is different from that of adult ischemic stroke where thrombolysis is a good op. METHODS We report a case of a 17-year-old male child presenting in emergency with an episode of acute ischemic stroke ...

Alteplase has traditionally been the only pharmacologic agent available for treating acute ischemic stroke worldwide, and is considered an effective and safe therapeutic drug for acute cerebral ischemia. However, the drug is usually indicated for use in patients aged <81 years due to insufficient literature regarding the drug's safety in older individuals. Nevertheless, the elderly can benefit ...

conclusions due to considerable inter- and intra- heterogeneity among studies performed by other centers such as differences in study project, background, and population features, determining a pharmacotherapy model based on safe implementation of treatments in stroke or sits seem advantageous. results age, time of onset, systolic blood pressure, diabetes, stroke severity, co-morbidities and pr...

background: we intended to investigate the serum magnesium impact upon the disability after ischemic stroke. methods: a total of 67 ischemic stroke patients who less than 6 hours had passed from their attacks participated in this cross sectional study. we have measured their serum magnesium level and determined its correlation with their rankin disability score (rds) in the first 72 hours (rds0...

BACKGROUND Vertebral artery origin (VAO) stenosis is occasionally observed in patients who have acute ischemic stroke. We investigated the long-term outcomes and clinical significance of VAO stenosis in patients with acute ischemic stroke. METHODS We performed a prospective observational study using a single stroke center registry to investigate the risk of recurrent stroke and vascular outco...