backround and aim: in the present time, analgesic and anti-inflammatory drugs such as nonseroidal anti-inflammatory drugs and opioid compounds are used for the releif of pain, but due to their side effects and economical issues, the significance of research on finding analgesic drugs with less side effects and their ability to substitute these synthetic drugs and substituting newer analgesic co...

Acute pain may be defined as pain that is present in patients because of preexisting diseases, the surgical procedure or the combination of disease or surgery related sources.1 It may be the worst experience in a life of patient, as most of them perceive it the most ominous aspect of surgery. Inadequate postoperative pain relief is associated with increase in morbidity and mortality after surge...

BACKGROUND Randomised controlled trial evidence indicates that Alexander Technique is clinically and cost effective for chronic back pain. The aim of this mixed methods evaluation was to explore the role and perceived impact of Alexander Technique lessons in the naturalistic setting of an acute hospital Pain Management Clinic in England. METHODS To capture changes in health status and resourc...

introduction: acute coronary syndrome accounts for more than 15% of the chest pains. recently, hess et al. developed north american chest pain rule (nacpr) to identify very low-risk patients who can be safely discharged from emergency department (ed). the present study aimed to validate this rule in eds of two academic hospitals. methods: a prospective diagnostic accuracy study was conducted on...

appendicitis is the most common abdominal disease that requires surgery in the emergency ward. it usually presents as right lower quadrant pain, but may rarely present as left upper quadrant (luq) pain due to congenital anatomical abnormalities of the intestine. we report a patient who complained of persistent luq abdominal pain and was finally diagnosed by computed tomography (ct) as congenita...

the parafascicular nucleus (pfn) of thalamus, as a supraspinal structure, has an important role in processing of nociceptive information. in addition, μ-opioid receptor contributes to supraspinal modulation of nociception. in the present study, the effects of microinjection of naloxone (a non-specific opioid-receptor antagonist) and naloxonazine (a specific μ-opioid receptor antagonist) were in...

background & aim: ovarian torsion is one of the most common causes of emergency surgery in gynecology, with a tendency to occur in postmenopausal women. the aim of this study was to provide information concerning the clinical presentations, surgical management, pathological findings and risk of malignancy in postmenopausal women with ovarian torsion. methods:in this cross-sectional study, the r...

AIM To assess Acute Pain Service and paediatric pain management efficacy in a UK specialist paediatric hospital to inform wider recommendations for future sustainability. BACKGROUND UK paediatric acute pain services vary. Although comprehensive pain management guidelines exist, consensus on the best model of care is lacking. Worldwide, medical and pharmacological advances and rapid patient tu...