PURPOSE OF REVIEW Sepsis elicits profound changes in the concentrations of plasma proteins synthesized by liver parenchymal cells referred to as acute-phase proteins. Mechanisms controlling this orchestrated response include release of cytokines that induce acute-phase proteins, while other 'house-keeping' genes are downregulated. RECENT FINDINGS Although some acute-phase proteins help to con...

Transplantation of Yoshida sarcoma (solid type) and Zajdela ascites hepatoma tumors in rats induces a biphasic change in the concentration of the following five acute-phase proteins: alpha-1-acid glycoprotein; alpha-1-antitrypsin; haptoglobin; hemopexin; and ceruloplasmin. These proteins and other plasma proteins were quantitated by two-dimensional immunoelectrophoresis relative to normal serum...

Acute phase proteins are synthesized by the liver in response to acute response. While these insignificant healthy animals, their concentrations increase rapidly during infection, inflammation, or tissue damage and used as an indicator of inflammation. Since blood importance levels clinically important differ according animal species, they evaluated separately for each species. Most have been s...

BACKGROUND Vitamin A deficiency adversely affects child morbidity and survival. This deficiency is estimated by measurement of plasma retinol concentrations, but because plasma retinol is reduced by clinical and subclinical infection, this proxy measure can lead to overestimation. Infection and trauma are accompanied by rises in concentrations of acute-phase proteins in plasma. We aimed to esti...

This study aimed to compare the hemato-biochemical parameters in cats suffered from FLUTD with those of healthy cats, and evaluate inflammatory process by measuring serum amyloid A, alpha-1-Acid glycoprotein, plasma fibrinogen concentrations. Cats frequently suffer feline lower urinary tract disease (FLUTD), which causes acute renal failure, electrolyte buildup, acid-base imbalance. Acute-phase...