A previously healthy Japanese girl aged 4 years suddenly developed idiopathic nephrotic syndrome (INS) associated with acute renal failure (ARF). Despite prompt initiation of hemodialysis and prednisolone treatment, her ARF did not recover. A percutaneous renal biopsy performed within a month from the onset of INS revealed lesions of end-stage kidney, which is unusual for the acute stage of INS...

BACKGROUND Malaria has protean clinical manifestations and acute renal failure (ARF) is one of its serious complications and could be life threatening. This study was carried out to describe the clinical characteristics and factors associated with adverse out come in patients with malarial acute renal failure. METHODS Data of 46 Patients with ARF and smear positive malaria was analyzed furthe...

BACKGROUND The study aimed to investigate the clinical characteristics of acute renal failure (ARF) caused by oral acyclovir. METHODS A 45-year-old Chinese male patient with acyclovir-induced ARF suffered from abdominal pain for one day. The pain was extended to the epigastric area from the right lower quadrant. Transient oliguria was seen in addition to microscopic hematuria and proteinuria....

OBJECTIVE Acute renal failure (ARF) is one of the most common causes of death in patients with severe acute pancreatitis (SAP). Here, we aimed to investigate the risk factors of ARF in patients with SAP, assess the prognosis of patients with SAP and ARF, and seek potential measures to prevent ARF. METHOD A cross-sectional study was performed to analyze the data from patients with SAP. Both un...

BACKGROUND AND OBJECTIVES Relatively little is known about clinical outcomes, especially long-term outcomes, among patients who have chronic kidney disease (CKD) and experience superimposed acute renal failure (ARF; acute on chronic renal failure). DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS We tracked 39,805 members of an integrated health care delivery system in northern California who we...

No matter in which clinical field you will be working in the future, you will be confronted with cases of acute renal failure. In this acute emergency illness, various pathomechanisms come together and lead to a principally reversible decrease in renal function, often involving disbalances of water and electrolytes. The different types of acute renal failure have to be understood well in order ...

No matter in which clinical field you will be working in the future, you will be confronted with cases of acute renal failure. In this acute emergency illness, various pathomechanisms come together and lead to a principally reversible decrease in renal function, often involving disbalances of water and electrolytes. The different types of acute renal failure have to be understood well in order ...

background: renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. the aim of this study was to determine the final outcome of renal involvement in leptospirosis. methods: this longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. all patients we...

Acute renal failure (ARF) is a major worldwide cause of morbidity and mortality, lacking specific targeted, effective therapies. Renal tubular cell apoptosis has been recognized to play a critical role in the pathogenesis of ARF, yet few studies have evaluated whether intervention in apoptotic pathways can ameliorate the deterioration in renal function associated with ARF. Using transgenic mice...

KEY CLINICAL MESSAGE Acute renal failure (ARF) secondary to severe malaria is uncommon. We report a case of a patient visiting Africa for the first time presenting with malaria and ARF. There was complete recovery after hemodialysis. Early initiation of hemodialysis proves to be useful in restoration of renal function.