INTRODUCTION The current markers of disease activity in Takayasu arteritis (TA) are insufficient for proper assessment. We investigated circulating levels of unacylated and acylated ghrelin, leptin and adiponectin and their relationships with disease activity in patients with TA. METHODS This study included 31 patients with TA and 32 sex-, age- and body mass index-matched healthy controls. Di...

BACKGROUND AND OBJECTIVES The prevalence of obesity in Indonesia has increasing. We have assessed the relationship between plasma acylated ghrelin hormone and self-reported appetite ratings (hunger and desire to eat) in obese and normal weight men. METHODS AND STUDY DESIGN Thirty-two men participated in an experimental study, where acylated ghrelin and self-reported appetite ratings were comp...

Acylated anthocyanins from a purple-fleshed sweet potato (PFSP), obtained by organic cultivation in Brazil, were characterized after separation high performance liquid chromatography-diode array detector (HPLC-PDA). These manually collected at the output, concentrated and injected into resolution mass spectrometer (ESI-QTOF-MS2). Twenty-two acylated detected. Among them, sixteen had been report...

Escherichia coli acetyl coenzyme A carboxylase (ACC), the first enzyme of the fatty acid biosynthetic pathway, is inhibited by acylated derivatives of acyl carrier protein (ACP). ACP lacking an acyl moiety does not inhibit ACC. Acylated derivatives of ACP having chain lengths of 6 to 20 carbon atoms were similarly inhibitory at physiologically relevant concentrations. The observed feedback inhi...

It has come to the attention of the authors of " Proteomic analysis of protein palmitoylation in adipocytes " (Adipocyte 2013; 2(1): 17–27) that references 33, 47, 48, and 50 were incorrect. The correct references are listed below. Proteomic profiling of S-acylated macrophage proteins identifies a role for pal-mitoylation in mitochondrial targeting of phospholipid scramblase 3. MR. Proteome sca...

Complex antigens require processing within antigen-presenting cells (APCs) to form T cell stimulatory complexes with CD1 antigen-presenting molecules. It remains unknown whether lipids with multi-acylated moieties also necessitate digestion by lipases to become capable of binding CD1 molecules and stimulate T cells. Here, we show that the mycobacterial tetra-acylated glycolipid antigens phospha...

7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine (1) is a privileged chemical scaffold with significant biological activities. However, the currently accessible chemical space derived from 1 is rather limited. Here we expanded the chemical space related to 1 by developing efficient methods for regioselective monoacylation at N1 , N3 and N7 , respectively. With this novel methodology, a focused library ...

(Phytochemistry, 26, 2418 (1987)) Acylated Luteolin Glucosides from Salix gitgiana. MIzuo MIzuNo*, MAsAyA KATo, MuNEKAzu IINuMA, TosHIyuKI TANAKA, ' ARIKA KIMuRA, HIRoyosHI OHAsHI, HIDEKI SAKAi Besides apigenin and luteolin 7-glucoside, four novel glucosides acylated with acetic, trans-cinnamic, P-coumaric and ferulic acids, respectively were isolated from the leaves of Salix gitgiana (Salicace...

Foliar application has been studied to enhance grape composition and, therefore, wine quality. This work examined, for first time, the effects of foliar applications methyl jasmonate (MeJ) and plus urea (MeJ+Ur) Tempranillo vineyard on phenolic, aromatic nitrogen over two vintages (2019 2020). A reduction in alcoholic degree was observed MeJ MeJ+Ur wines. The effect treatments season-dependent....