Introduction: Paraneoplastic syndromes are frequently found in lung cancer and they can be the first manifestation of disease. We present the case of a patient with small cell lung cancer and two simultaneously paraneoplastic syndromes. Clinical case: A 63 year old male patient presented with anorexia, confusion and vomiting. Laboratory investigations exhibited severe hyponatremia with high uri...

Cushing's syndrome due to exogenous steroids is common, as about 1% of the general populations use exogenous steroids for various indications. Although endogenous Cushing's syndrome due to ectopic adrenocorticotropic hormone from a pancreatic neuroendocrine tumour is rare, a correct and early diagnosis is important. The diagnosis and management require high clinical acumen and collaboration bet...

Adrenocorticotropic Hormone Stimulation During Adrenal Vein Sampling To the Editor: We read with interest the article by Seccia et al,1 which investigated the effect of adrenocorticotropic hormone stimulation during adrenal vein sampling on the identification of lateralized aldosterone excess in primary aldosteronism. The authors concluded that a high or an intermediate dose of adrenocorticotro...

Glucocorticoids are well known for altering bone structure and elevating fracture risk. Nevertheless, there are very few reports on pelvic ring fractures, compared to other bones, especially with a predominantly ligamentous insufficiency, resulting in a rotationally unstable pelvic girdle. We report a 39-year-old premenopausal woman suffering from an atraumatic symphysiolysis and disruption of ...

Abbreviations: BC: Before Christ; UV: Ultraviolet; NCBI: National Center For Biotechnology Information; Mirna: Microrna; IL-1: Interleukin 1; MSH: Melanocyte Stimulating Hormone; ACTH: Adrenocorticotropic Hormone; LH: Luteinizing Hormone; FSH: Follicle-Stimulating Hormone; MC1R: Melanocortin Type 1 Receptor; ER: Estrogen Receptor ; PR :Progesterone Receptor; TPO: Thyroid Peroxidase; TSH: Thyroi...

OBJECTIVE Aneurysmal subarachnoid hemorrhage puts patients at high risk for the development of pituitary insufficiency. We evaluated the incidence of pituitary dysfunction in these patients and its correlation with clinical outcome. METHODS Pituitary function was tested in 66 consecutive patients in the first 15 days after aneurysmal subarachnoid hemorrhage. The following were measured in all...