OBJECTIVE With the use of any drug comes the possibility of unintended consequences which when harmful are referred to as adverse drug reactions (ADRs). The development of national pharmacovigilance systems is the responsibility of all health workers. The aim of this study was to investigate the knowledge of nurses about pharmacovigilance and attitudes about ADR and adverse event reporting. M...

BACKGROUND Adverse drug reactions (ADRs) cause significant morbidity and mortality. Improved assessment of ADRs to identify the causal relationship, the severity, and the preventability will aid ADRs prevention or reduce patient burden. OBJECTIVE The aim of this study was to develop mobile apps in assisting clinical decision in ADR assessments of causality, severity, and preventability using ...

background : following establishment of iranian adverse drug reaction (adr) monitoring  center  in  1997, adr  committees  were  established  in  all  hospitals  of mazandaran province of iran. clinical pharmacists from mazandaran university of medical sciences have been involved with these committees since 2007. the aim of this study was to compare the results of the pharmacovigilance system b...

Background: Postmarket drug safety surveillance largely depends on spontaneous reports by patients and healthcare providers, hence less common adverse drug reactions—especially those caused by long‐ term exposure, multidrug treatments, or specific to special populations—often elude discovery. Objective: Here we propose an ultra‐low‐cost fully automated method for continuous monitoring of advers...

BACKGROUND Pharmacovigilance is the "science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug related problems". Nepal joined the international pharmacovigilance programme as a full member in 2007. KIST Medical College, Lalitpur, Nepal joined the national programme as a regional centre from mid-July 2008. Currently, the patt...

Objective: Adverse drug reactions (ADRs) are a well-known cause of hospital Abstract admission. Nevertheless a quantitative estimate of the preventability of and physicians' awareness of these reactions is lacking. Study Design and Methods: Using intensive bedside and computer-assisted drug surveillance methods a 13-month prospective pharmacoepidemiological survey was carried out on patients ad...

Background: In India, spontaneous reporting of adverse drug reactions (ADRs) by healthcare professionals was initiated in 2010. The drug safety issues for geriatric population are critical due to age-related physiological changes, pharmacodynamics and pharmacokinetics changes. Objective: Our objective was to assess the spontaneous reports of adverse drug reactions, observed in geriatric patient...

179 Many countries run schemes which encourage physicians and other health care professionals to report suspected drug reactions (ADRs). The aims of these spontaneous reporting schemes (SRSs) are to identify previously unsuspected reactions, to elucidate the relevant risk factors, and to evaluate the comparative toxicity of drugs within the same therapeutic class [1,2]. By their nature these sc...

To investigate the association between NAT2 genotypes and the incidence of isoniazid (INH)-induced adverse reactions, in the hope of identifying a pharmacogenetic approach that could be useful in the prediction and prevention of adverse reactions in Japanese patients, we retrospectively studied the genotypes of NAT2 in 102 Japanese patients treated with INH (without rifampicin co-administration...

Adverse drug reactions (ADRs) to phenformin and metformin reported to the Swedish Adverse Drug Reaction Committee during 1965--77 were analysed in relation to sales and prescription data. The biguanides accounted for 0.6% of all reported adverse drug reactions but for 6% of the fatal cases (all phenformin). Sixty-four ADRs to phenformin and eight to metformin were classified as causal relation ...