Adhesion molecules such as vascular cell adhesion molecule-1 (VCAM-1) play an important role during the early stages of atherogenesis. Agastache rugosa has an anti-atherogenic effect in low density lipoprotein receptor -/- mice. Moreover, A. rugosa reduced macrophage infiltration and VCAM-1 expression has been localized in aortic endothelium that overlies early foam cell lesions. This study asc...

We cloned the gene of d-limonene synthase (ArLMS) from Agastache rugosa (Labiatae). The function of ArLMS was elucidated by the preparation of recombinant protein and subsequent enzyme assay. ArLMS consisted of 2077 nucleotides including 1839 bp of coding sequence that encodes a protein of 613 amino acids. This protein has a 60 kDa molecular weight, which is identical to that of d-limonene synt...

Transient receptor potential ankyrin1 (TRPA1) and transient receptor potential vanilloid 1 (TRPV1) are members of the TRP superfamily of structurally related, nonselective cation channels and mediators of several signaling pathways. Previously, we identified methyl syringate as an hTRPA1 agonist with efficacy against gastric emptying. The aim of this study was to find hTRPA1 and/or hTRPV1 activ...

The effect of acetone extracts of Foeniculum vulgare Mill., seeds at different dose levels (50/ug, 150/ug and 250/ug/100gm body wt.) on mammary glands and oviducts of castrated rats was investigated. The extract was found to increase nucleic acids and protein concentration as well as the organ weights in both the tissues. The medium and high doses were very effective. The results confirm the es...

anise hyssop is a prennial herb belonging to the lamiaceae family. essential oil of this plant is used in food, pharmaceuticals, cosmetics industries as well as flavoring liqueurs. since water stress affects the growth, productivity, as well influences the active principles governing medicinal plants, in this research the effect of different water deficit stresses on such morphological traits a...

net photosynthesis rate (pn), stomatal conductance (gs) and transpiration rate (e) of anise hyssop were measured during the four cloudless days, in reference to diurnal fluctuations of leaf temperature (tleaf), leaf vapor pressure deficit (vpd leaf) and photosynthetic photon flux density (ppfd) in well watered (ww), stressed (s) and recovered (r) plants. an analysis of measured data showed that...