Mutations in the WNT10A gene were first detected in the rare syndrome odonto-onycho-dermal dysplasia (OODD, OMIM257980) but have now also been found to cause about 35-50% of selective tooth agenesis (STHAG4, OMIM150400), a common disorder that mostly affects the permanent dentition. In our random sample of tooth agenesis patients, 40% had at least one mutation in the WNT10A gene. The WNT10A Phe...

Congenital agenesis of lumbar vertebrae was diagnosed in a day-old female lamb based on radiology and clinical examinations. There was no neurological deficit in hindlimb and forelimb associated with standing disability. Radiography of the abdominal region revealed absence of lumbar vertebrae. Necropsy confirmed clinical and radiographic results. No other anomaly or agenesis was seen macroscopi...

AMA Jarka J, Angerman A. Agenesis of permanent canines – observation carried out on own material. Clinical aspects. Forum Ortodontyczne / Orthodontic Forum. 2023;19(1):7-25. doi:10.5114/for.2023.130175. APA Jarka, J., & Angerman, (2023). Forum, 19(1), 7-25. https://doi.org/10.5114/for.2023.130175 Chicago Jolanta, and Adam Mieczysław Angerman. 2023. "Agenesis aspects". 19 (1): Harvard pp.7-25. M...

CONTEXT Agenesis of the dorsal pancreas is a rare developmental anomaly. This anomaly may be complicated by recurrent acute and chronic pancreatitis. CASE REPORT We report the case of a 28-year-old female with agenesis of the dorsal pancreas and chronic calcific pancreatitis. The diagnosis of agenesis of the dorsal pancreas is discussed and the genetic changes leading to it are reviewed. The ...

Agenesis of the gallbladder, a rare anomaly, is generally regarded as an organogenic failure. Several reports suggest that this congenital defect is inherited but that supposition remains controversial. We described agenesis of the gallbladder in identical twins. A 21-year-old female presented with a history of acute pain in the epigastrium and right hypochondrium. Various imaging modalities sh...

The absence of a cerebellum is extremely rare condition and the clinical presentation is variable. We aimed to present a case with isolated cerebellar agenesis in a pregnant woman at 23 weeks of gestation. Twenty seven years old primigravid patient was referred to our obstetrics outpatient clinic with a suspicion of cerebellar in her fetus. Cerebellum agenesis has been identified by ultrasound ...

Tooth agenesis is the most common dental anomaly. The aim of this retrospective study was to identify common patterns of tooth agenesis in a sample of 92 patients (55 females and 37 males; mean age 27.7 years) with non-syndromic severe hypodontia. The Tooth Agenesis Code (TAC) procedure was used for that purpose. The patients in this study were missing between 6 and 22 permanent teeth (mean 11....

INTRODUCTION Genital abnormalities have been reported in up to 12 percent of men with unilateral renal agenesis.(1) There have also been reports of neurofibromatosis patients manifesting ipsilateral renal agenesis.(2) Abnormal development of the mesonephric duct between the fourth and thirteenth week of embryonic life seems to be the origin of such cysts, which can have a variable clinical pres...

CONTEXT Agenesis of the dorsal pancreas is one of the rare congenital malformations of pancreas. The association of agenesis of the dorsal pancreas with pancreatic tumors is extremely rare and only around 9 cases being reported till date. CASE REPORT We report a case of a fifty one year old woman with an agenesis of the dorsal pancreas with periampullary pancreaticobiliary adenocarcinoma. She...

Individuals with cleft lip and palate present significantly more dental anomalies, even outside the cleft area, than do individuals without clefts. Our aim was to evaluate the prevalence of tooth agenesis and patterns of hypodontia in a large sample of patients with complete bilateral cleft lip and palate (BCLP). Serial panoramic radiographs (the first radiograph was taken at 10.5-13.5 yr of ag...