Open Access The tremendous advancement in medical research in USA owes much to the Flexner's report in 1910 which suggested making the scientific research an essential component of medical curriculum. 1 National Institute of Health (NIH) of the United States during 1946-50, put the biomedical research as its top priority and faculty was encouraged to implant the " virus of curiosity and inquiry...

Across many domains, end-users need to compose computational elements into novel configurations to perform their day-to-day tasks. End-user composition is a common programming activity performed by such end-users to accomplish this composition task. While there have been many studies on end-user programming, we still need a better understanding of activities involved in end-user composition and...

A particular application of the biopsychosocial model is associated in peer-reviewed literature and patient testimony with harms done to chronically ill disabled people. These derive from an empirically unsubstantiated, neoliberal narrative emphasising role personal responsibility effort ‘recovery’ ill-health, ignoring socio-structural contributors chronic illness disability. Notably, this igno...

Pulmonary arterial hypertension (PAH) is a debilitating progressive disease with a poor prognosis. The median survival for idiopathic pulmonary hypertension was 2.8 years: advances in specifically targeted therapeutics have improved the prognosis significantly, but mortality remains high. Irrespective of the cause of PAH, there is evidence of severe vascular endothelial dysfunction within the p...

BACKGROUND Advanced intercross lines (AIL) are segregating populations created using a multi-generation breeding protocol for fine mapping complex trait loci (QTL) in mice and other organisms. Applying QTL mapping methods for intercross and backcross populations, often followed by naïve permutation of individuals and phenotypes, does not account for the effect of AIL family structure in which f...

Anuradha Singh is a scientist with National Institute of Science, Technology and Development Studies (CSIR) doing research on the theory and practice of Ayurveda. She has authored a book and several research papers on crossroads of Science and Indian Medical Traditions, Philosophical Foundations of Classical Medical Theories and Maternal Health & Ayurveda. She is also a founder member of Lok Sw...