Y. Lemoigne and A. Caner (eds.), Radiation Protection in Medical Physics, NATO Science for Peace and Security Series B: Physics and Biophysics 1, DOI 10.1007/978-94-007-0247-9_2, © Springer Science+Business Media B.V. 2011 Abstract A number of radiation units exist for representing radiation dose to patients, staff, public and quantities for radiation equipment performance in radiological pract...

PURPOSE In high-dose-rate (HDR) brachytherapy (BT), the source dwell times and dwell positions are essential treatment planning parameters. An optimal choice of these factors is fundamental to obtain the desired target coverage with the lowest achievable dose to the organs at risk (OARs). This study evaluates relevant dose parameters in cervix brachytherapy in order to assess existing tandem-ri...

This article is a case report of a high grade, radio-induced, breast malignant fibrous histiocytoma (undifferentiated high grade pleomorphic sarcoma), which developed in a 44-year old female, seven years after breast conservative surgery and radiotherapy for a T1N0M0 invasive left breast ductal carcinoma. The sarcoma presented as a fast growing tumour, 9.5 cm in the largest diameter, with skin,...

Introduction The Gamma Knife system is designed solely for non-invasive treatment of brain disorders, and it benefits from stereotactic surgical techniques. Dose calculations required in the system are performed by GammaPlan code; in this code, brain tissue is considered uniform. In the present study, we evaluated the effect of Gamma Knife system on the obtained dose through simulating a real ...

PURPOSE To develop a robust technique for detecting blood oxygenation level-dependent (BOLD) contrast in the human breast and to evaluate the signal in healthy and malignant breast. MATERIALS AND METHODS The design of this study focused on determining the optimal pulse sequence and stimulus for detecting BOLD contrast in the breast. For this study a single-shot fast spin echo (SSFSE) sequence...

The objective of this theoretical study is to design an ultrasound (US) cylindrical phased array that can be used for hyperthermia (40-44 degrees C) treatment of tumours in the intact breast. Simultaneously, we characterize the influence of acoustic and thermal heterogeneities on the specific absorption rate (SAR) and temperature patterns to determine the necessity of using heterogeneous models...

introduction the gamma knife system is designed solely for non-invasive treatment of brain disorders, and it benefits from stereotactic surgical techniques. dose calculations required in the system are performed by gammaplan code; in this code, brain tissue is considered uniform. in the present study, we evaluated the effect of gamma knife system on the obtained dose through simulating a real h...

PURPOSE To compare intracavitary brachytherapy dose estimation for organs at risk (bladder and rectum) based on semi-orthogonal reconstruction of radiographs on non-isocentric X-ray unit and Computed Tomography (CT) - based volumetric planning in cervical cancer. MATERIAL AND METHODS Bladder and rectal points as per International Commission on Radiation Units and Measurements (ICRU) report 38...

The 25-kDa heat shock protein (Hsp25) is associated with various malignancies and is expressed at high levels in biopsies as well as circulating in the serum of breast cancer patients. In this study, we used RNA interference technology to silence the hsp25 gene in 4T1 breast adenocarcinoma cells, known as a poorly immunogenic, highly metastatic cell line. We demonstrate that transfection of 4T1...