Stroke in the infant and child, although not a new entity, is increasingly being recognized as one of the most common causes of morbidity in childhood, with reasonably consistent incidence figures of 2 to 3 per 100 000 population and suggested rates as high as 13 per 100 000.1,2 Importantly, stroke recurrence rates in children of 6% to as high as 40% have been reported in recent literature,3,4 ...

Magnetic resonance imaging (MRI) has long been recognized as a useful technique for guiding diagnostic and therapeutic procedures. Biopsies have been guided by MRI since the 1980s1; neurosurgery followed soon thereafter.2 Excellent soft tissue contrast and accurate spatial localization and display in 3 dimensions were particular advantages of MRI over other modalities in neurological and body i...

Cemento-ossifying fibroma (COF) is a bone producing, slow growing, asymptomatic, well-demarcated, benign lesion of the jaw.1 Typically affects female between 20 to 40 years, predilection for the mandible premolar-molar region, causing a painless swelling but undergoes slow expansile growth.2 Most probably tumor originates from periodontal membrane, therefore, with double embryonic origin (ectod...

Patients with heart failure and reduced ejection fraction account for about half of the 6 million patients with heart failure and the $35 billion spent annually on related medical costs. Over the past 25 years, heart failure management has evolved through randomized trials of specific therapy and the extensive clinical experience accumulated at referral centers, many of which arose initially to...

Recent study reports have described the health and mental health (MH) issues of US servicemembers involved inwartime deployments,1,2 including the toll on American lives. From October 2001 through May 2010, there have been 5473 American casualties and 38 076wounded in action.3 A recent study identified significant stress and MH problems in US Army wives whose husbands experienced deployments.4 ...

We analyzed linkage and chromosomal positions of genes in A. lyrata ssp. petraea that are located near the centromere (CEN) regions of A. thaliana, using at least two genes from the short and long arms of each chromosome. In our map, genes from all ten A. thaliana chromosome arms are also tightly linked in A. lyrata. Genes from the regions on the two sides of CEN5 have distant map localizations...

In April 2005, the US Food and Drug Administration (FDA) commented on the current research regarding the use of magnetic resonance imaging (MRI) on patients with a pacemaker or implantable cardioverter-defibrillator (ICD).1 Pacemaker and ICD labeling currently cautions physicians against the use of MRI, and MRI manufacturers contraindicate MRI for pacemaker and ICD patients. As discussed in our...

Where do intimal smooth muscle cells (SMCs) come from? For many years, the idea that intimal SMCs originated from the underlying media went unchallenged.1 Then, reports2,3 began to appear that up to half of the SMCs in the intima of atherosclerotic plaques and injured arteries arose from circulating progenitor cells of bone marrow origin. This new view of intimal SMC formation was potentially i...

In the May issue of the Journal, King and Moores1 presented a very nice overview of asthma phenotypes and disorders that mimic asthma. That article was followed by a paper by McCormack and Enright2 that reviewed the process of making a diagnosis of asthma, including a brief overview of the differential diagnosis of asthma. I respectfully submit that missing from both papers is a description of ...