Cluster Analysis for Large Scale Gene Expression Studies High throughput gene expression analysis is becoming more and more important in many areas of biomedical research. cDNA microarray technology is one very promising approach for high throughput analysis and provides the opportunity to study gene expression patterns on a genomic scale. Thousands or even tens of thousands of genes can be spo...

Alexander Borst studied Biology at the University of Wuerzburg. His PhD work in Martin Heisenberg’s lab demonstrated that the mushroom bodies of Drosophila are indispensable for olfactory learning. He did a postdoc with Karl Goetz at the Max-PlanckInstitute for biological Cybernetics in Tübingen, where he started to work on fly motion vision, a field which he never left since. In 1993, he becam...

silver coins of alexander of macedonia, until the arrival of parthians in the 1st century bc, have been put in wdxrf in order to determin ag, cu, pb and au as major and trace elements for fineness, debasement and refinement of silver in ancient persia. seleucid kingdom from 4th to 1st century bc was succeeded by several dynasties and kings. but the chemical composition of their silver coins an...

By considering a (not necessarily locally-flat) PL knot as the singular locus of a PL stratified pseudomanifold, we can use intersection homology theory to define intersection Alexander polynomials, a generalization of the classical Alexander polynomial invariants for smooth or PL locally-flat knots. We show that the intersection Alexander polynomials satisfy certain duality and normalization c...

Freedman, Lovász and Schrijver characterized graph parameters that can be represented as the (weighted) number of homomorphisms into a fixed graph. Several extensions of this result have been proved. We use the framework of categories to prove a general theorem of this kind. Similarly as previous resuts, the characterization uses certain infinite matrices, called connection matrices, which are ...

For a prime p and binomial axk+bxl with 1 ≤ l < k < 1 32 (p−1) 2 3 , we use Stepanov’s method to obtain the bound ∣∣∣∣∣ p−1 ∑ x=1 ep(ax k + bx) ∣∣∣∣∣ max { 1, l∆− 1 3 } 1 4 k 1 4 p 3 4 , where ∆ = k−l (k,l,p−1) .

Alexander disease is a fatal neurological illness characterized by white-matter degeneration and formation of Rosenthal fibers, which contain glial fibrillary acidic protein as astrocytic inclusion. Alexander disease is mainly caused by a gene mutation encoding glial fibrillary acidic protein, although the underlying pathomechanism remains unclear. We established induced pluripotent stem cells ...

This paper traces the history of Bioenergetic Analysis from origins in Freud’s psychoanalytic method, through development theory and technique working directly with body as introduced by Wilhelm Reich, then covers contributions Alexander Lowen, who created Analysis. The differences between Reich Lowen will be presented, well other body-oriented methods, why others, while valuable, are not compr...