Allergic conjunctivitis (AC), which may be acute or chronic, is associated with rhinitis in 30%-70% of affected individuals, hence the term allergic rhinoconjunctivitis (AR/C). Seasonal and perennial AC is generally milder than the more chronic and persistent atopic and vernal keratoconjunctivitis. Natural allergens like house dust mites (HDM), temperate and subtropical grass and tree pollen ar...

Atopic diseases which include bronchial asthma, allergic rhinitis, atopic dermatitis, and ocular allergic disorders are among the most frequent conditions experienced by patients. Allergic conjunctivitis, an atopic ocular disease, is one of the most common problems encountered in general ophthalmic practice and the only ocular inflammatory disease that represents a pure type-I hypersensitivity ...

Pollen is the most common aeroallergen to cause seasonal conjunctivitis. The result of allergen exposure is a strong Th2-mediated response along with conjunctival mast cell degranulation and eosinophilic infiltration. Oleanolic acid (OA) is natural a triterpene that displays strong anti-inflammatory and immunomodulatory properties being an active anti-allergic molecule on hypersensitivity react...

This case report details an association of chronic allergic conjunctivitis and respiratory tract colonization in a cystic fibrosis (CF) patient due to an ethmoidal mucocele infected with Escherichia coli. A 3-year-old CF patient presented for evaluation with complaints of chronic periocular erythema, conjunctival injection, and irritation for 2 years. He was treated for presumed allergic conjun...

PURPOSE To determine the contribution of conjunctival mast cells to the allergen-specific inflammatory responses in eyes with allergic conjunctivitis and to test the hypothesis that mast cells act as mediators of the early phase response. METHODS The participation of mast cells in allergen-induced inflammatory cell recruitment was studied in an experimental murine model of allergic conjunctiv...

PURPOSE To assess the prevalence of allergic conjunctivitis in Gambia and to determine its epidemiologic features, seasonal variations and associated ocular and systemic conditions. METHODS Records of patients clinically diagnosed with allergic conjunctivitis between April 2007 and March 2008 were reviewed. Variables including age, sex, date of presentation, and systemic and ocular findings w...

Background and Aim: The purpose of the present study is to provide a basis for use propolis as therapeutic agent allergic conjunctivitis. Methods: effect eye drops on experimental conjunctivitis in rats was investigated. occurred by sensitization challenge egg albumin number scratching, hyperemia, chemosis, vascular permeability histamine content conjunctival tissue tears were assayed. Results:...

This study investigated the effectiveness of tetrandrine (TDR) on experimental allergic conjunctivitis secondary to ragweed pollen. SWR/J mice were divided as follows: group 1, normal controls; group 2, sensitized but untreated; group 3, sensitized, buffered saline (BS)-treated; and group 4, sensitized, TDR-treated. The last three groups were exposed to ragweed through topical contact on the na...