In the analysis of respiratory tract reactions, much emphasis is placed on possible allergic mechanisms. The term "allergy" was introduced by von Pirquet in 1906 (1) to describe the profound biologic transformation of the intact organism resulting from adequate exposure to viable and nonviable agents, so that re-exposure, often to small, indeed minute, and apparently innocuous amounts of extrin...

About 10-15% of all adults report that they are allergic penicillin or other antibiotics, although the accuracy and significance these reports remain unclear. In the outpatient setting, clinicians face a dilemma in prescribing for patients with a history of an allergic reaction to antibiotics. Which drugs should these patients avoid? Are these patients at increased risk for an allergic reaction...

Immunization is highly effective in preventing infectious diseases and therefore an indispensable public health measure. Allergic patients deserve access to the same publicly recommended immunizations as non-allergic patients unless risks associated with vaccination outweigh the gains. Whereas the number of reported possible allergic reactions to vaccines is high, confirmed vaccine-triggered al...

Introduction: Allergic and irritant compounds are frequent in nature, and the environmental allergic factors which can induce or exacerbate eczema are different and often unknown in different areas. The aim of this study was to determine the frequency of contact dermatitis in patients with chronic dermatitis referring to dermatology clinics in kerman. Methods: In this descriptive study, standar...

The human immune system is an assemblage of cellular and humoral components working together in a highly complex, coordinated, and elegant fashion to achieve the primary goal of protecting the human host (self) from harmful offenders (nonself). Exposure to danger signals activates the various immune mechanisms to bring about immune responses aimed at neutralizing the dangerous nonself while pre...

Background Mast cells are activated during allergic reactions, releasing inflammatory mediators that include tryptase. This process leads to the symptoms of an allergic reaction. A transient increase in the total level of serum tryptase indicates mast cell activation, e.g. an anaphylactic reaction. This may help to confirm and assess the extent of a systemic reaction. In the current study, the ...

Introduction: Chronic rhinosinusitis (CRS) is a multifactorial disease. Allergies are considered a predisposing factor to CRS; however, this remains controversial. The objective of this research was to investigate the prevalence of co-morbidities and allergic reaction, and to specify the most common allergens in patients with confirmed CRS.   Materials and Methods: One hundred patients with sig...

enythromycin is believed to cause no serlous reactions after large doses, nausea, rarely vomiting and occasionally abdominal pain and diarrhea may occur, (herrell, 1954). according to' kagan and faller (1955) no allergic reaction to' erythromycin has been reported. phlebitis and thrombosis have been observed, (shoe maker & yow, 1954). in a report by solomon and johnson, (1955) toxic reactions w...

The discovery of drugs for the treatment of inflammatory allergic diseases such as, asthma, allergic rhinitis, and sinusitis is a very important subject in human health. Gallic acid (3,4,5-trihydroxybenzoic acid), a polyphenyl natural products from gallnut and green tea, is known to have anti-oxidant, anti-inflammatory, anti-microbial, and radical scavenging activities. The aim of the present s...

Why is it important to know the percentage of people with food allergy in the community? Individuals with food allergy develop symptoms after eating foods that for the vast majority of the population are part of a healthy diet. The only way for the allergic individual to manage food allergy is to avoid eating the food that causes the allergic reaction. The level of avoidance required may seriou...