Incidence and Natural History Ventricular septal defect is the commonest congenital heart lesion in childhood and probably accounts for 20% of all heart defects (Keith, Rowe, and Vlad, I958). It has been reported to be the second most common cause of death in children suffering from heart disease (Zacharioudakis, Terplan and Lambert, 1957). An accurate appraisal of the life-span of a child born...

Determinations of the blood serum levels of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha) and their soluble receptors (sIL-6R, sTNFR) in denture stomatitis patients (DS) were performed. Serum levels of interleukins and their soluble receptors were measured using the ELISA method. In all examined patients mycological diagnostics were conducted using API 20C AUX stripe tests and a...

Limb-girdle muscular dystrophy type 2D (LGMD-2D) is caused by autosomal recessive defects in the alpha-sarcoglycan gene located on chromosome 17q21. In this study, we present a child with alpha-sarcoglycanopathy and describe a novel deletion in the alpha-sarcoglycan gene. A 5-year-old boy had a very high serum creatinine phosphokinase level, which was determined incidentally, and a negative mol...

A 7-month-old female child was diagnosed to have a massive right atrial aneurysm, presented with arrhythmias. She was treated by restorative right atrioplasty without using cardiopulmonary bypass. She had good postoperative outcome and a 5-month follow-up remains uneventful. In the absence of major congenital heart defects, aneurysm of right atrium can be treated without using cardiopulmonary b...

A case of progressive pulmonary hypertension in a child with a small ventricular septal defect is presented. Natural history studies have indicated that children with small ventricular septal defects can be followed conservatively. This case represents a contradiction to that rule and suggests that further study must be directed toward defining the etiology of pulmonary hypertension in patients...

INTRODUCTION The latest achievements in molecular diagnosis create new possibilities for evaluation of congenital abnormalities. AIM To present our preliminary experience with genetic diagnosis of congenital combined conotruncal heart defects. METHODS The analysis comprised 35 families with more than one member suffering from conotruncal heart defects (Group I) and 10 families (Group II) ha...

Alcoholic liver disease is associated with injury ranging from steatosis to steatohepatitis, fibrosis and cirrhosis. One of the mechanisms organs damage cytokines influences. The intensity depends on individual reactivety.The aim study was evaluate changes in blood interleukins heart high- low-emotional (HE, LE) male rats ethanol hepatosis, hepatitis, cirrhosis determine degree damage.Material ...

background: to determine the prevalence and characteristics of birth defects in perinatal infants in hubei province during 200l-2008. methods: the prevalence of birth defects in perinatal infants delivered after 28 weeks or more was analyzed in hubei surveillance hospitals during 200l-2008. results: the incidence of birth defects in perinatal infants from 200l to 2008 was 120.0 per 10,000 birth...