In classical kinetic or kinetic-like models a particle free path distribution is exponensial, but this is more likely to be an exception than a rule. In this paper we derive a linear Boltzmann-like equation for a general free path distribution in the framework of Alt’s model J. Math. Biol. 9, 147 (1980). In the special case that the free path distribution has at least first and second finite mo...

During the last 50 years, mechanization of the rural environment, and more recently the Common Agricultural Policy have led to deep changes in the agrarian landscapes across Europe, and with special relevancy in the case of mediterranean landscapes (Pinto-Correia et al., 2004). In the north-east of the Iberian Peninsula, a small area of enclosures landscape persists as a relict of what had been...

Alternative lengthening of telomeres (ALT) is a telomerase independent telomere maintenance mechanism that occurs in ∼15% of cancers. The potential mechanism of ALT is homology-directed telomere synthesis, but molecular mechanisms of how ALT maintains telomere length in human cancer is poorly understood. Here, we generated TERC (telomerase RNA) gene knockouts in telomerase positive cell lines t...