Photopolymerized hydrogels are extensively investigated for various tissue engineering applications, primarily due to their ability to form hydrogels in a minimally invasive manner. Although photocrosslinkable hydrogels provide necessary biological and chemical characteristics to mimic cellular microenvironments, they often lack sufficient mechanical properties. Recently, nanocomposite approach...

Porous nanospheres have a wide range of applications such as in catalysis, separation and controlled delivery. Among these nanospheres, syntheses and applications of porous silica nanospheres have been investigated extensively. Uniform porous silica nanospheres can be synthesized using a modified Stöber method. In the present study, porous silica spheres were prepared in the pre-formed emulsion...

Following a study on the feasibility of resonance energy transfer (RET) from carboxylated nanospheres with an incorporated phosphorescent donor to a cationic polyelectrolyte/acceptor aggregate on their surface, a novel scheme for homogeneous assays is presented that is based on RET from phosphorescent biotinylated nanospheres to fluorescently labeled streptavidin (SA). The phosphorescent nanosp...

We develop a strategy for preparing water-based dispersions of polymer/TiO₂ nanospheres that can be used to form composite materials applicable in various fields. The formed hybrid nanospheres are monodisperse and possess a hierarchical structure. It starts with the primary TiO₂ nanoparticles of about 5 nm, which first assemble to nanoclusters of about 30 nm and then are integrated into monomer...

Luminescent mesoporous Tb(OH)3@SiO2 core-shell nanospheres were synthesized through W/O microemulsion process at ambient temperature. The negatively charged silica favors a coating of the positively charged Tb3+ composite. Thus, silicon layer was adsorbed on the surface of Tb(OH)3 groups to form Tb-O-Si through electrostatic interaction. X-ray diffraction, field emission transmission electron m...

We developed nanospheres of crosslinked networks of methacrylic acid grafted with poly(ethylene glycol), and acrylic acid grafted with poly(ethylene glycol) nanospheres for use as oral insulin delivery devices. The copolymer nanospheres were synthesized via free-radical precipitation/dispersion. The average particle diameter of the copolymer gel nanospheres at various physiologically relevant p...

Bupropion is an atypical antidepressant drug. Fluctuating in its serum levels following oral administration of immediate release dosage forms leads to occasional seizure. The aim of the present work was designing of sustained release bupropion HCl nanospheres suited for pulmonary delivery. Agar nanospheres were prepared by transferring the w/o emulsion to solid in oil (s/o) suspension. Calcium ...

In this work, we present a detailed investigation of the magnetic properties of cobalt nanospheres grown on cantilever tips by focused electron beam induced deposition (FEBID). The cantilevers are extremely soft and the cobalt nanospheres are optimized for magnetic resonance force microscopy (MRFM) experiments, which implies that the cobalt nanospheres must be as small as possible while bearing...

In this work we propose two novel sensing principles of detection that exploit the magnetic dipolar Mie resonance in high-refractive-index dielectric nanospheres. In particular, we theoretically investigate the spectral evolution of the extinction and scattering cross sections of these nanospheres as a function of the refractive index of the external medium (next). Unlike resonances in plasmoni...

We present a facile method for the preparation of polyethyleneglycol diacrylate (PEG-DA) hydrogels with plasmonic gold (Au) nanospheres incorporated for various biological and chemical sensing applications. Plasmonic Au nanospheres were prepared ex situ using the standard citrate reduction method with an average diameter of 3.5 nm and a standard deviation of 0.5 nm, and evaluated for their surf...