In addition to cytotoxic effects, anticancer agents can exert multiple immunomodulatory functions. We have recently described the molecular mechanisms whereby bleomycin can 1) promote endoplasmic reticulum stress, causing the immunogenic death of cancer cells and hence strengthening antitumor CD8+ T cell responses; and 2) induce the secretion of transforming growth factor β (TGFβ), which stimul...

Daily pleasant or stressful experiences with grown children may contribute to parental well-being. This diary study focused on midlife parents' (N = 247) reports regarding grown children for 7 days. Nearly all parents (96%) had contact with a child that week via phone, text, or in person. Nearly all parents shared laughter or enjoyable interactions with grown children during the study week. Mor...

Weight fluctuations pose serious challenges to people's health. Research suggests that the interplay between cognitive dietary restraint and counter-regulative overeating impairs weight control. In a random sample from the general population (N = 2733, 49% male), a longitudinal survey was conducted over 4 consecutive years (2010-2013). Self-reported weight was used to calculate the variance of ...

Article history: Received 31 August 2015 Revised 28 November 2015 Accepted 30 November 2015 Available online 2 December 2015 The ability of attitudinal ambivalence and certainty to individually predict an attitude's stability over time has received mixed support. We proposed that ambivalence and certainty moderate one another's relationship with temporal attitude stability. That is, we hypothes...

Ambivalence is widely assumed to prolong grief. To examine this hypothesis, the authors developed a measure of ambivalence based on an algorithmic combination of separate positive and negative evaluations of one's spouse. Preliminary construct validity was evidenced in relation to emotional difficulties and to facial expressions of emotion. Bereaved participants, relative to a nonbereaved compa...

CONTEXT Ambivalence in pregnancy intentions is well-documented in sub-Saharan African (SSA) settings and has been associated with inconsistent use of contraception, thereby exposing women using contraception to the possibility of unintended pregnancies. A better understanding of the potential role for client counseling interventions in enabling women to achieve their pregnancy intentions is ess...

This article compares the first two Dutch translations of Qur’an printed in Republic: De Arabische Alkoran (1641) published by Barent Adriaensz Berentsma and Mahomets (1657) Jan Rieuwertsz. It builds upon previous bibliographic research quantifying abbreviation Surahs editions, identifying sources paratexts, describing different strategies for translation. analysis reveals how editing choices r...

OBJECTIVE Ambivalence can be understood as a cyclical movement between an emerging narrative novelty-an Innovative Moment (IM)-and a return to a problematically dominant self-narrative. The return implies that the IM, with its potential for change is devalued right after its emergence. Our goal is to test the hypothesis that the probability of the client expressing such form of ambivalence decr...