Bioactive polymeric materials based on calcium phosphates have tremendous appeal for hard tissue repair because of their well-documented biocompatibility. Amorphous calcium phosphate (ACP)-based ones additionally protect against unwanted demineralization and actively support regeneration of hard tissue minerals. Our group has been investigating the structure/composition/property relationships o...

Maryam Nabiyouni, Sarit B Bhaduri. University of Toledo, Toledo, OH 43606 Statement of Purpose: Nonviral gene delivery has gained much attention due to its potential in addressing the viral gene delivery limitations like unintentional mutagenesis. Different natural and synthetic materials such as polymers, lipids, and calcium phosphate particles have been developed as DNA carriers. However, the...

A plasma- and precursor-assisted biomimetic process utilizing plasma and alternate dipping treatments was applied to a Leed-Keio artificial ligament to produce a thin coating of apatite in a supersaturated calcium phosphate solution. Following plasma surface modification, the specimen was alternately dipped in calcium and phosphate ion solutions three times (alternate dipping treatment) to crea...